Table 4 Multivariate analysis for factors impacting toxicity

High comorbidity index

2.74 (1.25–5.99)

2.08 (1.05–4.21)

P value

.01

.03

Every-3-weeks chemotherapy

24.38 (3.00–198.03)

1.16 (0.41–3.26)

P value

.003

.20

Post-operative RT

0.60 (0.29–1.24)

0.66 (0.34–1.25)

P value

.17

.20

Cisplatin

6.38 (0.78–52.31)

1.94 (0.67–5.78)

P value

.08

.22

Age ≥ 60

0.59 (0.29–1.22)

1.64 (0.85–3.23)

P value

.60

.14