From: Influence of age on voice quality after transoral CO2 laser microsurgery
Voice quality outcomes | 1-month postoperative | Group | 3-month | Group | 6-month | Group | 12-month | Group | ||||
---|---|---|---|---|---|---|---|---|---|---|---|---|
 < 60 yo |  ≥ 60 yo | p-value |  < 60 yo |  ≥ 60 yo | p-value |  < 60 yo |  ≥ 60 yo | p-value |  < 60 yo |  ≥ 60 yo | p-value | |
VHI | 48.0 ± 41.1 | 46.3 ± 29.6 | NS | 33.3 ± 21.9 | 19.8 ± 20.3 | 0.007 | 27.7 ± 22.5 | 16.3 ± 18.3 | 0.030 | 28.0 ± 21.7 | 12.2 ± 14.5 | 0.001 |
GRBAS | ||||||||||||
 Grade of dysphonia | 2.0 ± 0.8 | 2.2 ± 0.7 | NS | 1.8 ± 0.9 | 1.8 ± 0.8 | NS | 1.4 ± 0.9 | 1.5 ± 0.8 | NS | 1.4 ± 0.9 | 1.5 ± 0.9 | NS |
 Roughness | 1.4 ± 0.7 | 1.5 ± 0.9 | NS | 1.4 ± 0.9 | 1.4 ± 0.8 | NS | 1.3 ± 0.7 | 1.3 ± 0.7 | NS | 1.0 ± 0.7 | 1.3 ± 0.8 | NS |
 Breathiness | 1.7 ± 0.9 | 1.7 ± 0.8 | NS | 1.3 ± 0.9 | 1.2 ± 0.9 | NS | 1.1 ± 0.9 | 1.0 ± 0.7 | NS | 1.1 ± 0.8 | 0.8 ± 0.7 | NS |
 Asthenia | 0.1 ± 0.2 | 0.1 ± 0.5 | NS | 0.2 ± 0.5 | 0.1 ± 0.2 | NS | 0.1 ± 0.1 | 0.1 ± 0.1 | NS | 0.1 ± 0.1 | 0.1 ± 0.2 | NS |
 Strain | 1.1 ± 0.9 | 1.1 ± 0.9 | NS | 0.8 ± 0.8 | 1.0 ± 0.9 | NS | 0.8 ± 0.9 | 0.8 ± 0.8 | NS | 0.8 ± 0.9 | 0.6 ± 0.7 | NS |
Acoustic measures | ||||||||||||
 F0 (Hz) | 154.4 ± 52.8 | 171.5 ± 43.8 | NS | 158.2 ± 51.5 | 168.0 ± 44.0 | NS | 156.7 ± 44.4 | 155.9 ± 38.9 | NS | 156.2 ± 49.4 | 154.8 ± 38.0 | NS |
 STD (Hz) | 5.4 ± 4.7 | 9.8 ± 12.6 | NS | 6.8 ± 9.6 | 6.5 ± 5.7 | NS | 5.9 ± 14.5 | 4.0 ± 2.4 | NS | 7.4 ± 13.8 | 4.3 ± 4.2 | NS |
 Jitter (%) | 3.6 ± 4.0 | 3.7 ± 3.1 | NS | 3.5 ± 3.2 | 2.8 ± 2.4 | NS | 3.0 ± 3.9 | 2.7 ± 2.6 | NS | 2.7 ± 2.9 | 2.7 ± 2.8 | NS |
 Shimmer (%) | 7.0 ± 4.0 | 8.2 ± 5.7 | NS | 7.4 ± 4.6 | 6.7 ± 4.6 | NS | 6.2 ± 3.8 | 7.3 ± 5.4 | NS | 6.7 ± 4.4 | 7.7 ± 6.3 | NS |
 NHR | 0.2 ± 0.1 | 0.2 ± 0.1 | NS | 0.2 ± 0.1 | 0.2 ± 0.1 | NS | 0.2 ± 0.1 | 0.2 ± 0.1 | NS | 0.2 ± 0.1 | 0.2 ± 0.1 | NS |
Maximum phonation time | 9.8 ± 4.6 | 11.6 ± 5.8 | NS | 9.9 ± 5.3 | 11.5 ± 7.5 | NS | 10.9 ± 5.4 | 10.5 ± 5.1 | NS | 11.2 ± 5.6 | 11.2 ± 6.0 | NS |
Fluency | 141.0 ± 19.2 | 138.2 ± 22.8 | NS | 143.5 ± 19.0 | 136.9 ± 22.9 | NS | 149.0 ± 19.0 | 139.5 ± 19.8 | NS | 147.7 ± 19.7 | 140.1 ± 19.1 | NS |
Mucosal wave | 1.5 ± 2.1 | 2.3 ± 1.5 | NS | 2.7 ± 0.5 | 1.7 ± 1.1 | NS | 2.1 ± 0.9 | 1.6 ± 0.9 | NS | 1.6 ± 1.1 | 1.6 ± 0.9 | NS |