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Table 2 Comparison of patient characteristics between two outcome groups

From: Cyclin D1 overexpression is associated with poor prognosis in oropharyngeal cancer

  Total (N = 60) Group 1a(N=39, 65%) Group 2a(N = 21, 35%) P value
Mean age at diagnosis (yr ± SD) 60.4 ± 11.7 59.8 ± 11.3 61.4 ± 12.6 0.63
Gender     
  Male 46 (77) 30 (77) 16 (76)  
  Female 14 (23) 9 (23) 5 (24) 1
Smoking Habit     
  Non-smokers 14 (23) 10 (26) 4 (19) 0.78
  Former smokers (quit > 5 yr) 15 (25) 9 (23) 6 (29)  
  Current smokers 29 (48) 20 (51) 9 (43)  
  Unknowne 2 (3) 0 (0) 2 (10)  
Alcohol b     
  Never or light 51 (85) 34 (87) 17 (81) 1
  Heavy 7 (12) 5 (13) 2 (10)  
  Unknowne 2 (3) 0 (0) 2 (10)  
T staging     
  1 25 (42) 19 (49) 6 (29) 0.44
  2 15 (25) 9 (23) 6 (29)  
  3 12 (20) 6 (15) 6 (29)  
  4 3 (5) 2 (5) 1 (5)  
  Unknowne 5 (8) 3 (8) 2 (10)  
N staging     
  N0 7 (12) 6 (15) 1 (5) 0.4
  N+ 51 (85) 32 (82) 19 (90)  
  Unknowne 2 (3) 1 (3) 1 (5)  
TNM staging c     
  1 2 (3) 2 (5) 0 (0) 0.61
  2 4 (7) 3 (8) 1 (5)  
  3 11 (18) 6 (15) 5 (24)  
  4 41 (68) 27 (69) 14 (67)  
  Unknowne 2 (3) 1 (3) 1 (5)  
Treatment information     
  Surgery (S/T) only 3 (5) 2 (5) 1 (5) 0.12
  Radiation (XRT) onlyd 30 (50) 18 (46) 12 (57)  
  Chemotherapy only 11 (18) 5 (13) 6 (29)  
  Combined S/T and XRT 16 (27) 14 (36) 2 (10)  
Mean Follow-Up Time (yr ± SD) 4 ± 2.4 4.7 ± 2.2 2 ± 1.6 < 0.0001
  1. aOutcome: Group 1, those survived with no disease or died due to other cause (disease-free survival); Group 2, those alive with disease or died of disease (progress-free survival or disease-specific deaths).
  2. bHeavy alcohol intake was defined as > 3 drinks/day for males and > 2 drinks/day for females.
  3. cTNM staging is based on the American Joint Committee on Cancer (AJCC) Cancer Staging Manual. 7th ed 2010.
  4. dRadiation only include radiation only with/without induction chemotherapy.
  5. eMissing values (Group 1 (N): Group 2 (N)): Smoking Habit (0:2), Alcohol (0:2), T-staging (3:2); Nodal Status (1:1); TNM staging (1:1).