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Table 3 Comparison of tumour HPV DNA, p16 and cyclin D1 status between outcome groups 1 and 2

From: Cyclin D1 overexpression is associated with poor prognosis in oropharyngeal cancer

  Total (N=60) Group 1 (N=39, 65%) Group 2 (N=21, 35%) P value
HPV-HR     
  Positive 23 (56) 14 (61) 9 (50) 0.54
  Negative 18 (44) 9 (39) 9 (50)  
HPV-16/18     
  Positive 15 (37) 8 (35) 7 (39) 1
  Negative 26 (63) 15 (65) 11 (61)  
p16     
  Positive 27 (66) 16 (70) 11 (61) 0.74
  Negative 14 (34) 7 (30) 7 (39)  
Cyclin D1     
  Positive 12 (29) 4 (17) 8 (44)  
  Negative 29 (71) 19 (83) 10 (56) 0.09