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Table 1 Chi-squared analysis of p16, Ki67, EGFR, p53, and Bcl-xL with nodal disease at presentation and development of distant metastases in OPSCC patients treated with all modalities from 2002–2009

From: Molecular predictors of locoregional and distant metastases in oropharyngeal squamous cell carcinoma

Biomarker

Nodal disease at presentation

Development of distant metastases

 

x 2

p-value

x2

p-value

p16

12.480

0.000**

0.225

0.748

Ki67

0.410

0.737

1.830

0.189

EGFR

0.870

0.427

0.793

0.508

p53

3.407

0.092

0.548

0.561

Bcl-xL

4.915

0.039**

0.113

0.852

  1. **Denotes statistical significance.