Prognostic utility of basaloid differentiation in oropharyngeal cancer

Table 1 Clinicopathologic characteristics, staging, and treatment of patients based on p16 and basaloid differentiation stratification

Characteristic	All	B	NB	P	+P16	-P16	P
n	208	84	124	-	111	97	-
Mean age	58.4	57.4	59.1	0.28	55.3	62.0	<0.01
Gender (male)	161	64	97	0.73	88	73	0.49
P16 Status
Positive	111	69	42	<0.01	-	-	-
Negative	97	15	82		-	-
Staging (%)
Advanced	91	94	89	0.19	97	84	<0.01
Early	9	6	11		3	16
T Staging (%)
T1	19	23	17	<0.01	21	17	0.10
T2	27	36	21		28	26
T3	31	33	30		35	27
T4	23	9	33		16	31
N Stage (%)
N0	14	7	18	0.04	6	24	<0.01
N positive	86	93	82		94	76
Treatment (%)
Primary surgery	75	77	73	0.54	72	68	0.06
Primary RT	25	23	27		28	32
Surgery + CRT	37	52	27	<0.01	51	21	<0.01
Surgery + RT	23	14	28		19	27
CRT	17	17	18		14	21
RT	8	6	10		5	11
Surgery	15	11	18		10	21

n = number of patients. Primary RT = radiation therapy +/− Chemotherapy. Primary surgery = Surgery +/− radiation therapy +/− Chemotherapy. B = basaloid differentiated. NB = non-basaloid. CRT = chemoradiation. RT = radiation. P values calculated using χ²or Fisher’s exact test for categorical data and two tailed t-test for continuous data.

ISSN: 1916-0216