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Table 1 Clinicopathologic characteristics, staging, and treatment of patients based on p16 and basaloid differentiation stratification

From: Prognostic utility of basaloid differentiation in oropharyngeal cancer

Characteristic All B NB P +P16 -P16 P
n 208 84 124 - 111 97 -
Mean age 58.4 57.4 59.1 0.28 55.3 62.0 <0.01
Gender (male) 161 64 97 0.73 88 73 0.49
P16 Status        
Positive 111 69 42 <0.01 - - -
Negative 97 15 82   - -  
Staging (%)        
Advanced 91 94 89 0.19 97 84 <0.01
Early 9 6 11   3 16  
T Staging (%)        
T1 19 23 17 <0.01 21 17 0.10
T2 27 36 21   28 26  
T3 31 33 30   35 27  
T4 23 9 33   16 31  
N Stage (%)        
N0 14 7 18 0.04 6 24 <0.01
N positive 86 93 82   94 76  
Treatment (%)        
Primary surgery 75 77 73 0.54 72 68 0.06
Primary RT 25 23 27   28 32  
Surgery + CRT 37 52 27 <0.01 51 21 <0.01
Surgery + RT 23 14 28   19 27  
CRT 17 17 18   14 21  
RT 8 6 10   5 11  
Surgery 15 11 18   10 21  
  1. n = number of patients. Primary RT = radiation therapy +/− Chemotherapy. Primary surgery = Surgery +/− radiation therapy +/− Chemotherapy. B = basaloid differentiated. NB = non-basaloid. CRT = chemoradiation. RT = radiation. P values calculated using χ2or Fisher’s exact test for categorical data and two tailed t-test for continuous data.
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