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Table 2 Correlation of HPV status with patient and tumor factors

From: Does HPV type affect outcome in oropharyngeal cancer?

    All high-risk HPV HPV-16 only
Patient characteristic Total Negative Positive p* Negative Positive p*
Age <60 51 16 35 <0.001 18 33 <0.001
> = 60 44 29 15   32 12  
Gender Male 75 32 43 0.08 37 38 0.32
Female 20 13 7   13 7  
Subsite Tonsil   21 31 0.02 23 29 0.01
Base of Tongue   10 15   12 13  
Other   14 4   15 3  
T Classification 1 14 4 10 0.27 4 10 0.19
2 25 11 14   14 11  
3 30 18 12   19 11  
4 26 12 14   13 13  
N Classification 0 18 13 5 0.09 16 2 0.002
1 13 7 6   8 5  
2 54 21 33   22 32  
3 10 4 6   4 6  
Overal Stage 1 2 1 1 0.49 1 1 0.02
2 9 5 4   8 1  
3 13 8 5   10 4  
4 71 31 40   31 39  
Smoking never smokers 20 4 16 0.006 5 1 0.001
1-9 py 6 2 4   2 4  
10-19 py 6 1 5   1 5  
>20 py 57 35 22   39 18  
Unknown 6 3 3   3 3  
Alcohol < 21 drinks 70 30 40 0.37 34 36 0.45
(drinks/wk) >21 drinks 17 10 7   11 6  
Unknown 8 5 3   5 3  
Treatment CRT 62 29 33 0.78 30 32 0.55
Radiation 11 5 6   8 3  
Induction + CRT 13 5 8   6 7  
Surgery + CRT 5 3 2   3 2  
Surgery + RT 2 1 1   1 1  
Surgery 2 2 0   2 0  
HPV Type 16 45 0 45   0 45  
18 2 0 2   2 0  
33 1 0 1   1 0  
67 2 0 2   2 0  
p16 Negative 35 34 1 <0.001 34 1 <0.001
Positive 59 10 49   15 44  
  1. HPV human papillomavirus, py pack years, RT radiation, CRT chemoradiation.
  2. * Fisher exact test.