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Table 3 Comparison of HPV-16 and other high-risk (non-16) HPV types

From: Does HPV type affect outcome in oropharyngeal cancer?

   

HPV-Positive

 

Total

High-risk HPV (non-16)

HPV16

p*

Age

<60

35

2

33

0.15

> = 60

15

3

12

 

Gender

Male

43

5

38

1

Female

7

0

7

 

Subsite

Tonsil

31

2

29

0.33

Base of Tongue

15

2

13

 

Other

4

1

3

 

T Classification

1

10

0

10

0.58

2

14

3

11

 

3

12

1

11

 

4

14

1

13

 

N Classification

0

5

3

2

0.005

1-3

45

2

43

 

Overal Stage

1

1

0

1

<0.001

2

4

3

1

 

3

5

1

4

 

4

40

1

39

 

Smoking

never smokers

16

1

15

0.73

1-9 py

4

0

4

 

10-19 py

5

0

5

 

>20 py

22

4

18

 

Unknown

3

0

3

 

Alcohol

< 21 drinks

40

4

36

0.69

(drinks/wk)

>21 drinks

7

1

6

 

Unknown

3

0

3

 

Treatment

CRT

33

1

32

0.02

Radiation

6

3

3

 

Induction + CRT

8

1

7

 

Surgery + CRT

2

0

2

 

Surgery + RT

1

0

1

 

Surgery

0

0

0

 

p16

Negative

1

0

1

1

Positive

49

5

44

 
  1. HPV human papillomavirus, py pack years, RT radiation, CRT chemoradiation.
  2. * Fisher exact test.