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Figure 2 | Journal of Otolaryngology - Head & Neck Surgery

Figure 2

From: CO2 laser versus cold steel margin analysis following endoscopic excision of glottic cancer

Figure 2

Examples of histological grading system for artifact. A) None: Well preserved surface epithelium, seromucinous glands and stroma. B) Minor: Well preserved surface epithelium. Seromucinous glands show some indistinct hyperchromatic areas (arrow). C) Marked: Surface epithelium is partially denuded with remainder showing severe artifact (arrow). Lamina propria is relatively preserved and can be assessed for invasive carcinoma (asterisk). D) Uninterpretable: Fragmented margin tissue with detached surface epithelium (arrow) and indistinct fragments of lamina propria.

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