TY - JOUR AU - Brace, Matthew D. AU - Wang, Jun AU - Petten, Mark AU - Bullock, Martin J. AU - Makki, Fawaz AU - Trites, Jonathan AU - Taylor, S. Mark AU - Hart, Robert D. PY - 2014 DA - 2014/07/18 TI - Differential expression of transforming growth factor-beta in benign vs. papillary thyroid cancer nodules; a potential diagnostic tool? JO - Journal of Otolaryngology - Head & Neck Surgery SP - 22 VL - 43 IS - 1 AB - Thyroid nodules are common, but only 5% of nodules are found to be malignant. In North America, the incidence of thyroid cancer is increasing. Fine needle aspirate (FNA) biopsy is the diagnostic test of choice. Unfortunately, up to 20% of FNAs are non-diagnostic. A specific molecular marker for thyroid cancer is desirable. Evidence suggests that cell signaling through transforming growth factor beta (TGF- β) is important in the development of thyroid cancer. We sought to compare the expression of TGF- β in malignant and benign thyroid nodules. SN - 1916-0216 UR - https://doi.org/10.1186/s40463-014-0022-x DO - 10.1186/s40463-014-0022-x ID - Brace2014 ER -