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Table 2 Thyroid and nodule features in diagnostic and non-diagnostic thyroid FNA

From: Predictors of non-diagnostic cytology in surgeon-performed ultrasound guided fine needle aspiration of thyroid nodules

Variable

Diagnostic (n = 139)

Non-diagnostic (n = 41)

p-value

Thyroid dimensions

Enlarged

29%

33%

0.66

Not enlarged

71%

67%

Palpable

77%

64%

0.07

Nodule size

Average

23 mm (+/- 13 mm)

19 mm (+/- 15 mm)

0.25

>4 cm

10%

8%

0.8

<1 cm

18%

35%

0.02

Nodule location

Right

56%

49%

0.38

Left

44%

51%

Upper

24%

18%

0.8

Lower

55%

50%

0.35

Isthmus

22%

32%

0.55

Adverse features

Calcifications

22%

10%

0.1

Hypervascularity

49%

35%

0.14

Hypoechoic

15%

10%

0.59

Components

Solid

53%

43%

0.36

Cystic

11%

30%

0.001

Complex

37%

28%

0.33

  1. FNA = fine needle aspiration.
  2. “Enlarged” = at least one thyroid lobe greater than 6 cm in greatest dimension on ultrasound.
  3. Percentages are based on 131 patients, for a total of 180 nodules aspirated (139 diagnostic, 41 non-diagnostic).