Table 2 Sensitivity, specificity, positive and negative predictive value of each gene
From: Local molecular analysis of indeterminate thyroid nodules
Molecular Mutation | Number of Positive Cases | Malignant | Benign | Sp | Sn | PPV | NPV |
|---|---|---|---|---|---|---|---|
BRAF | 2 | 2 | 0 | 8.7 | 100 | 100 | 63.8 |
HRAS | 8 | 2 | 6 | 8.7 | 83.7 | 25 | 59.6 |
KRAS | 2 | 2 | 0 | 8.7 | 100 | 100 | 63.8 |
NRAS | 6 | 4 | 2 | 17.4 | 94.6 | 66.7 | 64.8 |
Overall | 18 | 10 | 8 | 43.5 | 78.4 | 55.5 | 69 |