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Table 2 Sensitivity, specificity, positive and negative predictive value of each gene

From: Local molecular analysis of indeterminate thyroid nodules

Molecular Mutation Number of Positive Cases Malignant Benign Sp Sn PPV NPV
BRAF 2 2 0 8.7 100 100 63.8
HRAS 8 2 6 8.7 83.7 25 59.6
KRAS 2 2 0 8.7 100 100 63.8
NRAS 6 4 2 17.4 94.6 66.7 64.8
Overall 18 10 8 43.5 78.4 55.5 69