Table 4 Cox regression model of various prognostic factors for disease specific survival
Variable | All patients | |||
|---|---|---|---|---|
Univariate analysis | Multivariate analysis | |||
RR (95 % CI) | p | RR (95 % CI) | p | |
Age | ||||
≤45 years | 1.05 (0.7–1.3) | 1.07 (0.8–1.3) | ||
≥45 years | 1.10 (0.8–1.4) | 0.6 | 1.10 (0.9–1.3) | 0.06 |
Gender | ||||
Female | 1.07 (0.9–1.4) | 1.05 (0.7–1.3) | ||
Male | 1.05 (0.7–1.3) | 0.6 | 1.40 (1.2–1.6) | 0.05 |
Histopathologic variants | ||||
Classic | 1.05 (0.7–1.2) | 1.20 (0.8–1.6) | ||
Follicular | 1.00 (0.6–1.8) | 1.18 (0.7–1.5) | ||
Hurthle cell | 1.30 (1.1–1.7) | 2.00 (1.6–2.4) | ||
Tall cell | 2.70 (1.6–4.5) | 2.82 (2.4–4.6) | ||
Sclerosing | 1.80 (1.6–2.9) | <0.0001 | 2.00 (1.6–3.0) | <0.0001 |
Multifocal | ||||
Yes | 3.1 (2.8–4.2) | 2.94 (2.2–3.4) | ||
No | 1.0 (0.8–1.2) | <0.0001 | 1.07 (0.9–1.3) | <0.0001 |
Surgical margins | ||||
Positive | 1.10 (0.9–1.4) | 1.20 (0.8–1.6) | ||
Negative | 1.07 (0.9–1.4) | 0.7 | 1.17 (0.6–1.2) | 0.68 |
ETE | ||||
Yes | 4.2 (3.5–5.1) | 3.31 (1.7–4.2) | ||
No | 1.05 (0.7–1.1) | <0.0001 | 1.17 (0.9–1.4) | <0.0001 |
LVSI | ||||
Yes | 2.0 (1.7–2.9) | 1.81 (1.6–2.8) | ||
No | 1.0 (0.8–1.2) | 0.02 | 1.04 (0.9–1.5) | 0.03 |
Lymph nodes | ||||
Positive | 4.45 (3.7–6.8) | 3.74 (3.4–5.9) | ||
Negative | 1.17 (0.9–1.4) | <0.0001 | 1.01 (0.8–1.3) | <0.0001 |
Mean postoperative TG | ||||
≤2 ng/ml | 1.01 (0.7–1.2) | 1.05 (0.7–1.2) | ||
>2 ng/ml | 1.04 (0.9–1.5) | 0.6 | 1.00 (0.6–1.8) | 0.6 |
RAI ablation | ||||
Yes | 0.35 (0.2–0.7) | 0.30 (0.2–0.8) | ||
No | 1.09 (1.0–1.9) | <0.0001 | 1.00 (0.6–1.8) | <0.0001 |