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Fig. 5 | Journal of Otolaryngology - Head & Neck Surgery

Fig. 5

From: In vivo Wnt pathway inhibition of human squamous cell carcinoma growth and metastasis in the chick chorioallantoic model

Fig. 5

WNT974 blocks liver metastasis of UM-SCC-11A and UM-SCC-25 CAM xenografts. Livers from UM-SCC-11A and -25 CAM xenografts (from Fig. 4) were harvested at the conclusion of the experiment and assessed for human ALU DNA sequences by qPCR. WNT974 was administered every other day to a final concentration of 1 μM. Livers from non-xenografted animals were used as a negative control and Ct difference from the median centered average of normal livers is shown. All qPCR assays were run in quadruplicate. ** P < 0.05

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Journal of Otolaryngology - Head & Neck Surgery

ISSN: 1916-0216

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