The role of transoral robotic surgery, transoral laser microsurgery, and lingual tonsillectomy in the identification of head and neck squamous cell carcinoma of unknown primary origin: a systematic review

Table 5 Identification rate of TORS/TLM in the presence of other findings

Author	Physical Exam		DI (CT/MRI)		PET/CT		PE/DI/PET-CT		EUA with biopsy
Author	+	-	+	-	+	-	+	-	+	-
Abuzeid et al. [26]	1/1 (100 %)	0/0 (0 %)	1/1 (100 %)	0/0 (0 %)	1/1 (100 %)	0/0 (0 %)	1/1 (100 %)	0/0 (0 %)	0/0 (0 %)	1/1 (100 %)
Blanco et al. [28]	-	-	-	-	-	-	-	-	-	-
Durmus et al. [18]	0/0 (0 %)	17/22 (77 %)	0/0 (0 %)	17/22 (77 %)	-	-	10/11 (91 %)	7/11 (64 %)^a	10/11 (91 %)	7/11 (64 %)
Karni et al. [16]	0/0 (0 %)	17/18 (94 %)	0/0 (0 %)	17/18 (94 %)	-	-	-	-	-	-
Mehta et al. [19]	0/0 (0 %)	9/10 (90 %)	0/0 (0 %)	9/10 (90 %)	4/4 (100 %)	5/6 (83 %)	4/4 (100 %)	5/6 (83 %)	0/0 (0 %)	9/10 (90 %)
Mourad et al. [27]	0/0 (0 %)	1/1 (100 %)	-	-	1/1 (100 %)	0/0 (0 %)	1/1 (100 %)	0/0 (0 %)	1/1 (100 %)	0/0 (0 %)
Nagel et al. [17]	0/0 (0 %)	31/36 (86 %)	-	-	-	-	-	-	-	8/14 (57 %)
Patel et al. [15]	-	-	-	-	-	-	18/26 (69 %)^b	13/18 (72 %)	0/0 (0 %)	11/18 (61 %)^c
Total	1/1 (100 %)	75/87 (86 %)	1/1 (100 %)	43/50 (86 %)	6/6 (100 %)	5/6 (83 %)	34/43 (79 %)	25/35 (71 %)	11/12 (92 %)	36/54 (67 %)

Abbreviations: DI diagnostic imaging, CT computed tomography, MRI magnetic resonance imaging, PE physical examination, PET positron emission tomography, EUA panendoscopic examination under anesthesia
^aNo suspicious findings on PET/CT, EUA, directed biopsies, or robotic exam
^bDenominator was calculated as 47 total patients minus 18 patients without positive findings minus three patients who did not undergo radiographic imaging before TORS
^cFailed deep tongue base biopsy

ISSN: 1916-0216