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Table 4 Relationship between HR HPV subtype and p16 over-expression

From: HPV DNA in saliva from patients with SCC of the head and neck is specific for p16-positive oropharyngeal tumours

  

p16 status

     

HR HPV status

Positive

Negative

p-value

Sen (95% CI)

Spe (95% CI)

PPV (95% CI)

NPV (95% CI)

Oropharynx

Positive

13

0

0.001

76 (50–93)

100 (59–100)

100 (75–100)

64 (30–89)

Negative

4

7

Non-oropharynx

Positive

5

2

0.002

80 (28–99)

93 (75–99)

67 (22–96)

96 (80–100)

Negative

1

25

  1. Abbreviations: HR HPV High right human papillomavirus, Sen Sensitivity, Spe Specificity, PPV Positive predictive value, NPV Negative predictive value