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Table 1 Assay performance by type of sample

From: Developing a new diagnostic algorithm for human papilloma virus associated oropharyngeal carcinoma: an investigation of HPV DNA assays

Test Sample type Sensitivity Specificity Area under curve (ROC)
Cobas® DNA FNA 91% 82% 0.86 (95% CI 0.75–0.93)
OP Swab 91% 36% 0.63 (95% CI 0.55–0.75)
Saliva 100% 69% 0.85 (95% CI 0.75–0.92)
Cervista® HR FNA 0% 90% 0.45 (95% CI 0.26–0.62)
OP swab 100% 33% 0.67 (95% CI 0.45–0.86)
Cervista® HPV Genotype FNA 0% 86% 0.43 (95% CI 0.25–0.61)
OP Swab 100% 14% 0.57 (95% CI 0.34–0.77)
  1. HPV Human papilloma virus, DNA Deoxyribonucleic acid, FNA Fine needle aspirate, OP Oropharyngeal