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Table 2 Associations of FOXp3 polymorphisms with RRP

From: Associations of FoxP3 gene polymorphisms with severe recurrent respiratory papillomatosis in Korean patients

  Total (n = 225) Male (n = 110) Female (n = 115)
Case  (n = 30) Control (n = 195)   Case (n = 15) Control
(n = 95)
  Case (n = 15) Control (n = 100)   
n (%) n (%) p n (%) n (%) p n (%) n (%) p OR (95% CI)
Age, mean
(range)
41.2
(4–80)
53.0
(41–71)
ns 42.5
(4–80)
55.1
(41–70)
ns 40.3
(7–69)
51.0
(41–71)
ns  
rs5902434
 del/del 15(50.0) 99(50.8) ns 10(66.7) 65(68.4) ns 5(33.3) 34(34.0) ns  
 del/ATT 10(33.3) 43(22.1) ns     10(66.7) 43(43.0) 0.043 3.1 (1.0–9.7)
 ATT/ATT 5(16.7) 53(27.2) ns 5(33.3) 30(31.6) ns 0(0.0) 23(23.0) 0.039 9.4 (1.1–163.1)
 del allele 30(66.7) 176(59.7) ns 10(66.7) 65(68.4) ns 20(66.7) 111(55.5) ns  
rs3761548
 CC 24(80.0) 141(72.3) ns 12(80.0) 81(85.3) ns 12(80.0) 60(60.0) ns  
 AC 3(10.0) 34(17.4) ns     3(20.0) 34(34.0) ns  
 AA 3(10.0) 20(10.3) ns 3(20.0) 14(14.7) ns 0(0.0) 6(6.0) ns  
 C allele 39(86.7) 235(79.7) ns 12(80.0) 81(85.3) ns 27(90.0) 154(77.0) ns  
rs3761549
 CC 20(66.7) 141(72.3) ns 13(86.7) 79(83.2) ns 7(46.7) 62(62.0) ns  
 CT 8(26.7) 33(16.9) ns     8(53.3) 33(33.0) ns  
 TT 2(6.7) 21(10.8) ns 2(13.3) 16(16.8) ns 0(0.0) 5(5.0) ns  
 T allele 35(77.8) 236(80.0) ns 13(86.7) 79(83.2) ns 22(73.3) 157(78.5) ns  
rs2232365
 AA 14(46.7) 100(51.3) ns 10(66.7) 66(69.5) ns 4(26.7) 34(34.0) ns  
 AG 11(36.7) 43(22.1) ns     11(73.3) 43(43.0) 0.028 3.6 (1.1–12.2)
 GG 5(16.7) 52(26.7) ns 5(33.3) 29(30.5) ns 0(0.0) 23(23.0) 0.039 9.4 (1.1–163.1)
 A allele 29(64.4) 177(60.0) ns 10(66.7) 66(69.5) ns 19(63.3) 111(55.5) ns  
  1. RRP recurrent respiratory papillomatosis,OR odds ratio, CI confidence interval