Table 2 Patient, tumor, and treatment data divided by treatment
Treatment A | Treatment B | p-value A vs B | Treatment C | |
|---|---|---|---|---|
Subjects, n | 36 | 25 | 7 | |
Age at diagnosis (years) | ||||
Mean (SD) | 56.6 (9.4) | 61.2 (10.9) | 0.12 | 67.1 (13.9) |
Median (range) | 57 (36–78) | 56 (45–87) | 63 (53–85) | |
Gender, male n (%) | 32 (89) | 20 (80) | 0.55 | 3 (43) |
Extracapsular extension | ||||
Yes | 11 (38) | 0 | 0 | |
No | 18 (62) | 8 (100) | 0.081 | 4 (100) |
p16 status | ||||
Positive | 28 (78) | 10 (63) | 3 (43) | |
Negative | 8 (22) | 6 (38) | 0.42 | 4 (57) |
N stage | ||||
N1 | 5 (14) | 6 (24) | 2 (29) | |
N2 | 22 (61) | 16 (64) | 5 (71) | |
N2a | 14 (39) | 6 (24) | 4 (57) | |
N2b | 8 (22) | 4 (16) | 1 (14) | |
N2c | 0 | 6 (24) | 0 | |
N3 | 9 (25) | 3 (12) | 0.84 | 0 |
Surgery | ||||
RND | 4 (11) | . | 1 (14) | |
Modified RND | 28 (78) | . | 4 (57) | |
SOND | 4 (11) | . | 2 (29) | |
Radiotherapy | ||||
Radiation schedule | ||||
I | 31 (86) | 18 (75) | . | |
II | 5 (14) | 1 (4) | . | |
III | 0 | 5 (21) | 0.011 | . |
Radiation to the pharynx | ||||
Pharynx incl. nasopharynx | 3 (9) | 10 (42) | . | |
Pharynx excl. nasopharynx | 33 (91) | 11 (46) | . | |
No radiation | 0 | 3 (13) | 0.0003 | . |
Radiation to the neck | ||||
Bilateral | 33 (91) | 20 (83) | . | |
Ipsilateral | 3 (9) | 4 (17) | 0.56 | . |
Chemotherapy | 6 (17) | 18 (72) | <0.0001 | . |