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Table 2 Mixed effects linear regression models for Speech Handicap Index (SHI)

From: Functional and quality of life outcomes after partial glossectomy: a multi-institutional longitudinal study of the head and neck research network

Subscale (n) Variable Estimate 95% CI SE t p SDs of Random Effects
Intercept Residual
SHI (n = 83) Baseline 20.86 15.6 to 26.2 2.71 7.69   16.86 16.14
1 month +9.98 +3.7 to +16.2 3.14 3.18 .002*   
6 month +9.24 +2.6 to +15.9 3.34 2.77 .006
1 year +7.66 +.4 to +14.8 3.69 2.08 .040
Psychosocial (n = 92) Baseline 8.46 5.8 to 11.0 1.32 6.41   8.70 7.93
1 month +4.31 +1.2 to +7.4 1.55 2.79 .006   
6 month +4.12 +.9 to +7.3 1.65 2.50 .013
1 year +4.04 +.5 to +7.6 1.80 2.25 .026
Speech (n = 92) Baseline 11.55 9.2 to 13.9 1.21 9.55   7.60 7.75
1 month +5.41 +2.7 to +8.1 1.36 3.96 <.001*   
6 month +4.65 +1.8 to +7.5 1.45 3.22 .002*
1 year +3.16 0 to +6.3 1.58 2.00 .048
  1. Note.*p < .0028; Baseline = pre-operative estimate of mean subscale scores for combined cohort; 1 month/6 months/1 year = difference between combined cohort mean subscale scores and baseline mean for the respective assessment time point; p-value for baseline scores not provided given that it tests the hypothesis that the baseline mean is significantly different from 0, results of which are not meaningful; 95% CI calculated using bootstrapping