Functional and quality of life outcomes after partial glossectomy: a multi-institutional longitudinal study of the head and neck research network

Table 3 Mixed effects linear regression models for M.D. Anderson Dysphagia Inventory

Subscale (n)	Variable	Estimate	95% CI	SE	t	p	SDs of Random Effects
Subscale (n)	Variable	Estimate	95% CI	SE	t	p	Intercept	Residual
Emotional (n = 112)	Baseline	79.40	75.3 to 83.5	2.08	38.25		9.38	12.27
	Sx-RT	−4.58	−10.4 to +1.3	2.94	−1.56	.122
	Sx-CRT	−8.64	−3.3 to −14.0	2.68	−3.22	.002*
	1 month	−6.45	−2.7 to −10.2	1.90	−3.39	<.001*
	6 month	−3.34	−7.2 to +.5	1.97	−1.69	.092
	1 year	−3.61	−7.9 to +.6	2.16	−1.67	.095
Functional (n = 112)	Baseline	84.32	79.6 to 89.0	2.38	35.48		11.70	12.93
	Sx-RT	−5.62	−12.3 to +1.2	3.45	−1.63	.107
	Sx-CRT	−13.08	−6.8 to −19.3	3.15	−4.15	<.001*
	1 month	−8.31	−4.4 to −12.3	2.02	−4.11	<.001*
	6 month	−5.95	−1.9 to −10.1	2.09	−2.85	.005
	1 year	−3.96	−8.5 to +.5	2.29	−1.73	.085
Physical (n = 112)	Baseline	77.85	73.4 to 82.3	2.29	34.05		11.01	12.75
	Sx-RT	−7.34	−.8 to −13.8	3.30	−2.23	.028
	Sx-CRT	−9.74	−3.9 to −15.5	3.01	−3.24	.002*
	1 month	−7.09	−3.3 to −11.0	1.99	−3.57	<.001*
	6 month	−3.58	−7.6 to +.5	2.06	−1.74	.084
	1 year	−3.46	−8.0 to +.9	2.25	−1.54	.126

Note. *p < .0028; Baseline = pre-operative mean estimate for surgery only group; Sx-RT,/Sx-CRT = difference between pre-operative mean scores and baseline for surgery and radiotherapy, and, surgery and chemoradiotherapy groups, respectively; 1 month/6 months/1 year = difference between mean subscale score and baseline for the respective assessment time point for combined cohort; p-value for baseline scores not provided given that it tests the hypothesis that the baseline mean is significantly different from 0, results of which are not clinically meaningful; 95% CI calculated using bootstrapping approach

ISSN: 1916-0216