Table 3 Multivariate analysis of risk factors in relation to disease-free survival
Univariate analysis | Multivariate analysis | |||
|---|---|---|---|---|
Variables | Hazard ratio (95% CI) | P-value | Adjusted hazard ratio (95% CI) | P-value |
Age (yr) | ||||
≤ 65 | 1 | 1 | ||
> 65 | 1.545 (0.528–4.520) | 0.427 | 1.670 (0.600–4.649) | 0.326 |
Sex | ||||
Female | 1 | 1 | ||
Male | 1.036 (0.477–2.250) | 0.929 | 1.841 (0.494–6.857) | 0.363 |
Clinical stage | ||||
I, II, III | 1 | 1 | ||
IV | 3.334 (1.217–8.129) | 0.019* | 2.059 (0.527–8.048) | 0.299 |
Surgery | ||||
No | 1 | 1 | ||
Yes | 0.231 (0.100–0.536) | 0.001* | 0.280 (0.091–0.857) | 0.026* |
Skull base invasion | ||||
No | 1 | 1 | ||
Yes | 2.750 (1.200–6.302) | 0.017* | 1.140 (0.253–5.146) | 0.865 |
Infratemporal fossa invasion | ||||
No | 1 | 1 | ||
Yes | 2.251 (1.098–5.789) | 0.029* | 2.259 (0.660–7.734) | 0.194 |
Cavernous sinus invasion | ||||
No | 1 | 1 | ||
Yes | 1.845 (0.725–4.693) | 0.198 | 1.083 (0.258–4.539) | 0.913 |