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Table 3 Multivariate analysis of risk factors in relation to disease-free survival

From: Cavernous sinus involvement is not a risk factor for the primary tumor site treatment outcome of Sinonasal adenoid cystic carcinoma

  Univariate analysis Multivariate analysis
Variables Hazard ratio (95% CI) P-value Adjusted hazard ratio (95% CI) P-value
Age (yr)
  ≤ 65 1   1  
  > 65 1.545 (0.528–4.520) 0.427 1.670 (0.600–4.649) 0.326
Sex
 Female 1   1  
 Male 1.036 (0.477–2.250) 0.929 1.841 (0.494–6.857) 0.363
Clinical stage
 I, II, III 1   1  
 IV 3.334 (1.217–8.129) 0.019* 2.059 (0.527–8.048) 0.299
Surgery
 No 1   1  
 Yes 0.231 (0.100–0.536) 0.001* 0.280 (0.091–0.857) 0.026*
Skull base invasion
 No 1   1  
 Yes 2.750 (1.200–6.302) 0.017* 1.140 (0.253–5.146) 0.865
Infratemporal fossa invasion
 No 1   1  
 Yes 2.251 (1.098–5.789) 0.029* 2.259 (0.660–7.734) 0.194
Cavernous sinus invasion
 No 1   1  
 Yes 1.845 (0.725–4.693) 0.198 1.083 (0.258–4.539) 0.913
  1. Abbreviations: CI confidence interval
  2. *statistically significant