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Table 3 Characteristics of patients classified by nephrotoxicity caused by cisplatin
| Characteristics | Nephrotoxicity- | Nephrotoxicity+ | P value* | |
|---|---|---|---|---|
| Age | < 65 | 40 (42.6) | 12 (44.4) | 1.0000 |
| ≥ 65 | 54 (57.4) | 15 (55.6) | ||
| Sex | female | 13 (13.8) | 6 (22.2) | 0.3671 |
| male | 81 (86.2) | 21 (77.8) | ||
| Primary site | Hypopharynx | 23 (24.5) | 9 (33.3) | 0.4578 |
| Others | 71 (75.5) | 18 (66.7) | ||
| Ccr | < 120 mL/min | 86 (79.3) | 22 (20.4) | 0.1619 |
| ≥ 120 mL/min | 8 (61.2) | 5 (38.4) | ||
| Albumin | < 4 g/mL | 32 (34.4) | 12 (44.4) | 0.3674 |
| ≥ 4 g/mL | 62 (66) | 15 (55.6) | ||
| Aprepitant | – | 25 (26.6) | 18 (66.7) | 0.0002 |
| + | 69 (73.4) | 9 (33.3) | ||
| Regimen | Crystalloid-only | 41 (43.6) | 24 (88.9) | < 0.0001 |
| Magnesium-supplemented | 53 (56.4) | 3 (11.1) |
