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Table 1 Characteristics of patients experiencing locoregional recurrence (LRR) or distant metastasis (DM) as first adenoid cystic carcinoma recurrence

From: Mortality risk after clinical management of recurrent and metastatic adenoid cystic carcinoma

  Overall LRR DM p value
Characteristic 36 20 16  
Ethnicity
 White (incl. Hispanic) 25 (69.4%) 10 (50.0%) 15 (93.8%) 0.02
 Asian/Pacific-Islander 8 (22.2%) 7 (35.0%) 1 (6.3%)
 African-American 1 (2.8%) 1 (5.0%) 0
 Other 2 (5.6%) 2 (10.0%) 0
Female 24 (66.7%) 13 (65.0%) 11 (68.8%) 0.55
Male 12 (33.3%) 7 (35.0%) 5 (31.3%)
Initial Stage 0.38
 I-II 5 (22.7%) 1 (12.5%) 4 (28.6%)
 III-IV 15 (77.3%) 7 (87.5%) 10 (71.4%)
 Unknown 14 12 2
Initial Treatment
 Surgery 7 (19.4%) 6 (30.0%) 1 (6.3%) 0.08
 Surgery + PORT 29 (80.6%) 14 (70.0%) 15 (93.8%)
Age at recurrence, Median (IQR) 64 (44–74) 66 (47–76) 60 (42–70) 0.48
Months to recurrence after initial treatment, Median (IQR) 50 (16–88) 51 (15–108) 50 (18–77) 0.58
Low-risk 14 (38.9%) 9 (45.0%) 5 (31.3%) 0.31
High-risk 22 (61.1%) 11 (55.0%) 11 (68.8%)  
  1. IQR interquartile range, RT radiation therapy, PORT post-operative radiation therapy