Table 1 Multivariate logistic regression analysis - preoperative CEA levels and medullary thyroid cancer progression
From: Carcinoembryonic antigen levels correlated with advanced disease in medullary thyroid cancer
# of patients | Pre-Op CEA (ng/ml) | (95% CI) | P-value | |
|---|---|---|---|---|
Primary tumor size (mm) | ||||
1–9 | 3 | 3.36 | (1.7-10) | 0.01 |
10–19 | 7 | 6.42 | ||
20–29 | 5 | 16.54 | ||
30–39 | 8 | 168.63 | ||
40+ | 10 | 188.73 | ||
Stage | ||||
I | 5 | 2.7 | (3.8-130) | 0.04 |
II | 11 | 38.8 | ||
III | 3 | 15.7 | ||
IVa | 8 | 74.7 | ||
IVb | 1 | 128.1 | ||
IVc | 5 | 405.9 | ||
Metastasis | ||||
Locoregional | 12 | 20.55 | (−14.4–225.7) | 0.08 |
Distant | 6 | 405.83 | ||
Location of lymph node metastasis | ||||
Central | 30 | 36.1 | ||
Central + Lateral | 18 | 120.1 | (19–228) | 0.02 |
Central + Lateral + Contralateral | 12 | 162.31 | ||
Biomedical Cure | ||||
Yes | 17 | 48.3 | (8.5–244) | 0.03 |
No | 16 | 174.6 | ||
Mortality | ||||
Yes | 2 | 74.9 | (0.0006–0.0013) | < 0.001 |
No | 31 | 583.7 | ||