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Table 1 Baseline Patient Characteristics

From: The role of induction chemotherapy followed by surgery in unresectable stage IVb laryngeal and hypopharyngeal cancers: a case series

Characteristics Resectable qroup
N = 18 (%)
Unresectable group
N = 14 (%)
p-value
Age, year
 Mean (SD) 59.5 (3.13) 62.3 (3.29) 0.053
Sex
 Male 14 (77.8) 10 (71.4) 0.681
 Female 4 (22.2) 4 (28.6)  
Performance status
 0 12 (66.7) 7 (50) 0.341
 1 6 (33.3) 7 (50)  
Smoking
 Yes 12 (66.7) 10 (71.4) 0.773
 No 6 (33.3) 4 (28.6)  
Alcohol
 Yes 8 (44.4) 8 (57.1) 0.476
 No 10 (55.6) 6 (42.9)  
Primary site
 Larynx 9 (50) 3 (21.4) 0.098
 Hypopharynx 9 (50) 11 (78.6)  
TN stage
 T3 N3 6 (33.3) 5 (35.7) 0.888
 T4bN2 5 (27.8) 4 (28.6)  
 T4bN3 7 (38.9) 5 (35.7)  
Causes of unresectability
 Preveterbral fascia invasion 4 (22.2) 5 (35.7) 0.960
 Carotid artery encasement 12 (66.7.) 5 (35.7)  
 Preveterbral fascia invasion and carotid artery encasement 2 (11.1) 3 (21.4)  
 Mediastinal structure involvement 0 1 (7.1)  
Regimen
 TPF 11 (61.1) 3 (21.4) 0.080
 CP 3 (16.7) 5 (35.7)  
 PF 4 (22.2) 6 (42.9)  
Differentiation
 Poor 7 (38.9) 7 (50) 0.641
 Moderate 6 (33.3) 5 (35.7)  
 Well 5 (27.8) 2 (14.3)  
  1. TPF = docetaxel, cisplatin, and 5-fluorouracil, CP = carboplatin and paclitaxel, PF = cisplatin and 5-fluorouracil