Secretory carcinoma: the eastern Canadian experience and literature review

Forner, David; Bullock, Martin; Manders, Daniel; Wallace, Timothy; Chin, Christopher J.; Johnson, Liane B.; Rigby, Matthew H.; Trites, Jonathan R.; Taylor, Mark S.; Hart, Robert D.

doi:10.1186/s40463-018-0315-6

Journal of Otolaryngology - Head & Neck Surgery

Table 5 Literature review

From: Secretory carcinoma: the eastern Canadian experience and literature review

Study	Number of Patients	Tumor Location n (%)	Treatment n (%)	Initial Nodal Disease^b, n (%)	Survival % (cause; timing)	Recurrence n (%); timing	Regional metastasis n (%); timing	Distant metastasis n (%); location timing
Aizawa et al. 2016	1	Parotid: 1 (100)	Surgery: 1 (100)	0 (0)	100%	0 (0)	1 (100); 2 years	0 (0)
Baghai et al. 2017	10	Parotid: 9 (90) MSG: 1 (10)	Surgery: 10 (100) LND: 3 (30) ART: 4 (40) ACRT: 1 (10)	3 (30)	66% (DOD; 24 months, 18 months)	3 (30); 3, 5, 120 months	0	1 (10); bone 15 months
Balanza et al. 2015	1	Parotid: 1 (100)	Surgery: 1 (100)	0 (0)	100%	0 (0)	0 (0)	0 (0)
Boon et al. 2018	31	Parotid: 18 (58) SMG: 1 (3) MSG: 12 (39)	Surgery: 31 (100) LND: 4 (13) ART: 15 (48)	1 (3)	97% (DOC; 48 months)	1 (3); 50 months	0 (0)	0 (0)
Chiosea et al. 2012	36	Parotid: 26 (72) SMG: 3 (10) MSG: 7 (24)	Surgery: 36 (100)LND: 18 (50)ART: 5 (14)ACRT: 2 (6)	4 (11)	97% (DOD; time unknown)	3 (8); time unknown	0 (0)	1 (3); unknown
Cipriani et al. 2017	1	MSG: 1 (100)	Surgery: 1 (100)	0 (0)	0% (DOD; 3 months)	0 (0)	0 (0)	1 (100); lungs 2 months
Cooper et al. 2013	2	MSG: 2 (100)	Surgery: 2 (100)	0 (0)	100%	0 (0)	0 (0)	0 (0)
Din et al. 2016	11	Parotid: 7 (64)SMG: 3 (27)MSG: 1 (9)	Surgery: 10 (91)ART: 2 (18)ACRT: 2 (18)	2 (18)	91% (DOD; 5 years)	3 (38)^a; time unknown	0 (0)	0 (0)
Drilon et al. 2016	1	Parotid: 1 (100)	Surgery: 1 (100)ART: 1 (100)Revision Surgery: 3 procedureCrizotinibEntrectinib	0 (0)	100%	0 (0)	0 (0)	1 (100); lungs 5.5 years
Fakhoury et al. 2016	1	Parotid: 1 (100)	Surgery: 1 (100)	0 (0)	100%	0 (0)	0 (0)	0 (0)
Griffith et al. 2013	6	Parotid: 4 (67)SMG: 1 (17)MSG: 1 (17)	Surgery: 5 (83)LND: 3 (50)No treatment: 1 (17)	1 (17)	100%	0 (0)	0 (0)	0 (0)
Helkamaa et al. 2015	1	MSG: 1 (100)	Surgery: 1 (100)	0 (0)	100%	0 (0)	0 (0)	0 (0)
Higuchi et al. 2014	7	Parotid: 6 (86)SMG: 1 (14)	Surgery: 7 (100)ART: 1 (14)	0 (0)	100%	0 (0)	0 (0)	0 (0)
Hijazi et al. 2014	1	Parotid: 1 (100)	Surgery: 1 (100)	0 (0)	100%	0 (0)	0 (0)	0 (0)
Hwang et al. 2014	1	Parotid: 1 (100)	Surgery: 1 (100)	0 (0)	100%	0 (0)	0 (0)	0 (0)
Inaba et al. 2015	1	Parotid: 1 (100)	Surgery: 1 (100)	0 (0)	100%	0 (0)	0 (0)	0 (0)
Ito et al. 2015	14	Parotid: 9 (64)SMG: 1 (7)MSG: 4 (29)	Surgery: 14 (100)	2 (14)	100%	1 (20)^a; 90 months		0 (0)
Jackson et al. 2017	1	Parotid: 1 (100)	Surgery: 1 (100)	0 (0)	100%	0 (0)	0 (0)	0 (0)
Jung et al. 2013	13	Parotid: 11 (85)Unknown: 2 (15)	Surgery: 13 (100)ART: 2 (15)	0 (0)	100%	3 (23); 10–101 months (mean 44)	0 (0)	0 (0)
Jung et al. 2015	9	Parotid: 9 (100)	Unknown	Unknown	Unknown	3 (33); time unknown	0 (0)	0 (0)
Kratochvil et al. 2012	2	MSG: 2 (100)	Surgery: 2 (100)	0 (0)	100%	0 (0)	0 (0)	0 (0)
Laco et al. 2013	2	Parotid: 1 (50)SMG: 1 (50)	Surgery: 2 (100)	0 (0)	100%	0 (0)	0 (0)	0 (0)
Levine et al. 2014	1	Parotid: 1 (100)	Surgery: 1 (100)	0 (0)	100%	0 (0)	0 (0)	0 (0)
Luk et al. 2015	9	Parotid: 9 (100)	Surgery: 9 (100)LND: 1 (11)ART: 1 (11)	1 (11)	89% (DOD; 13 months)	0 (0)	1 (11); 12 months	0 (0)
Luo et al. 2014	1	MSG: 1 (100)	Surgery: 1 (100)ART: 1 (100)	1 (100)	100%	0 (0)	0 (0)	0 (0)
Majewska et al. 2015	7	Parotid: 6 (86)MSG: 1 (14)	Surgery: 7 (100)LND: 2 (29)ART: 2 (29)	3 (43)	71% (DOD; 20 months, 79 months)	2 (29); 4 months, 10 months	1 (14); 48 months	0 (0)
Mossinelli et al. 2018	1	Parotid: 1 (100)	Surgery: 1 (100)	0 (0)	100%	0 (0)	0 (0)	0 (0)
Ngouajio et al. 2017	1	Parotid: 1 (100)	Surgery: 1 (100)LND: 1 (100)	0 (0)	100%	0 (0)	0 (0)	0 (0)
Oza et al. 2016	3	Parotid: 3 (100)	Surgery: 3 (100)	0 (0)	100%	0 (0)	0 (0)	0 (0)
Rastatter et al. 2012	1	Parotid: 1 (100)	Surgery: 1 (100)LND: 1 (100)	1 (100)	100%	0 (0)	0 (0)	0 (0)
Salat et al. 2015	2	Parotid: 2 (100)	Surgery: 2 (100)LND: 1 (50)ART: 2 (100)	0 (0)	100%	0 (0)	0 (0)	0 (0)
Serrano-Arevalo et al. 2015	4	Parotid: 1 (25)SMG: 1 (25)MSG: 2 (50)	Surgery: 2 (50)Nothing: 2 (50)ART: 1 (25)	1(25)	100%	0 (0)	0 (0)	0 (0)
Shah et al. 2015	1	Parotid: 1 (100)	Surgery: 1 (100)	0 (0)	100%	0 (0)	0 (0)	0 (0)
Skalova et al. 2010	16	Parotid: 13 (81)MSG: 3 (19)	Surgery: 16 (100)ART: 7 (44)LND: 1 (6)	1 (6)	94% (DOD; 6 years)	3 (19), 6 months, 2 years, 6 years	1 (6); 86 months	1 (6); lungs 2 years
Skalova et al. 2014	3	Parotid: 3 (100)	Surgery: 3 (100)ART: 2 (67)LND: 1 (33)	0 (0)	0% (3 DOD; 20 months, 4 years, 6 years)	2 (66); 2 years, 6 years	2 (67); 20 months, 4 years	2 (67); dissemintated 20 months, 4 years
Skalova et al. 2018	10	Parotid: 7 (70)SMG: 2 (20)MSG: 1 (10)	Surgery: 9 (90)LND: 1 (10)ART: 1 (10)ACRT: 1 (10)Nothing: 1 (10)	1 (10)	78% (1 DOD; 2 years. 1 DOC; 3 years)^a	0 (0)	1 (11); time unknown	1 (11); bone 15 months
Stevens et al. 2015	14	Parotid: 9 (64)Thyroid: 1 (7)SMG: 1 (7)MSG: 3 (21)	Surgery: 12 (88)Nothing: 2 (14)ART: 3 (21)	2 (14)	100%	1 (7); 4 years	0 (0)	1 (7);lungs 4 years
Total	227	Parotid: 166 (73)Other: 61 (27)	Surgery: 211 (97)^cLND: 37 (17)ART: 56 (26)	24 (11)	93% (13 DOD, 2 DOC)^cMean time: 38 months^d	26 (12)	8 (4)	9 (4)Mean time: 30 months^c, ^d

ART adjuvant radiotherapy, ACRT adjuvant chemoradiotherapy, LND lymph node dissection, MSG minor salivary gland, SMG submandibular gland, DOD died of disease, DOC died of other causes
^astudy includes patients lost to follow up, ^b: category includes patients with clinically evident nodes, or those that had lymph node dissection, ^c: Jung et al. 2014 not included, ^d: Mean time dos not include Chiosea et al

Back to article page

ISSN: 1916-0216

Contact us

Submission enquiries: Access here and click Contact Us
General enquiries: info@biomedcentral.com