Table 1 Overview of the included studies
From: Free versus pedicled flaps for reconstruction of head and neck cancer defects: a systematic review
Article | Ref | Study type | MINORS Scorea | N total | n FF | n PF | Type of free flaps | Type of pedicled flaps | Defect / tumor location |
|---|---|---|---|---|---|---|---|---|---|
Sinha, 2017 [14] | A | Retrospective review | 20 | 517 | 384 | 133 | ALT, FibF, RFFF | PMMF, SCAIF, SMIF | N/A |
Goyal, 2017 [10] | B | Retrospective review | 18 | 797 | 589 | 208 | NA | PMMF, SCAIF, SMIF, TEMP, TRPF, DELT | Cutaneous/ skull base |
Oral cavity | |||||||||
Oropharynx | |||||||||
Larynx / hypopharynx | |||||||||
Mandibular | |||||||||
Sinonasal | |||||||||
Composite/multiple sites | |||||||||
Li, 2016 [15] | C | Retrospective review | 19 | 41 | 24 | 17 | RFFF | PMMF | Oral cavity |
Kozin, 2016 [5] | D | Retrospective review | 20 | 72 | 28 | 45 | RFFF, ALT | SCAIF | Cutaneous defect |
Parotid/temporal bone | |||||||||
Howard, 2016 [21] | E | Retrospective review | 18 | 31 | 9 | 16 | ALT | SMIF | Lateral skull base |
6 | PLDF | ||||||||
Geiger, 2016 [17] | F | Retrospective review | 20 | 105 | 50 | 55 | 39 RFFF, 3 ALT, 4 FibF, 2 theLDF, 2 SFF, 2 ORFF | 51 PMMF, 2 DIEP, 2 TPF | N/A |
Gao, 2016 [49] | G | Retrospective review | 16 | 60 | 34 | 26 | RFFF | PMMF | N/A |
Forner, 2016 [27] | H | Retrospective review | 20 | 21 | 12 | 9 | RFFF | SMIF | Oral cavity |
Oropharynx | |||||||||
Zhang S, 2015 [32] | I | Retrospective review | 19 | 37 | 15 | 12 | RFFF | SCAIF | Oral cavity |
Zhang X, 2014 [16] | J | Retrospective review | 19 | 110 | 79 | 31 | ALT | PMMF | Oral cavity |
Oropharynx | |||||||||
Jing, 2014 [22] | K | Retrospective review | 17 | 49 | 22 | 27 | GFMF | PMMF | Larynx |
Granzow, 2013 [7] | L | Retrospective review | 18 | 34 | 16 | 18 | FFF | SCAIF | Larynx / hypopharynx |
Parotid | |||||||||
Oral cavity | |||||||||
Esophagus | |||||||||
Deganello, 2013 [11] | M | Retrospective review | 18 | 36 | 16 | 20 | RFFF | 10 TEMP, 10 PMMF | Oral cavity |
Oropharynx | |||||||||
Fang, 2013 [12] | N | Retrospective review | 18 | 56 | 20 | 24 | RFF | PLTM | Oral cavity |
12 | ALT | ||||||||
Paydarfar, 2011 [23] | O | Retrospective review | 20 | 60 | 33 | 27 | RFF | SMIF | Oral cavity |
Hsing, 2011 [25] | P | Retrospective review | 18 | 100 | 42 | 58 | N/A | PMMF | Oral cavity |
Chan Y, 2011 [35] | Q | Prospective review | 18 | 202 | 24 | 92 | ALT | PMMF | Hypopharynx |
86 | FJF | ||||||||
Demirtas, 2010 [18] | R | Retrospective review | 20 | 20 | 12 | 8 | 10 ALT, 2 LDF | PLDF | N/A |
O’Neil, 2010 [30] | S | Retrospective review | 20 | 114 | 77 | 37 | RFFF | PMMF | N/A |
Mallet, 2009 [6] | T | Retrospective review | 18 | 70 | 25 | 45 | 18 RFFF, 3 LD, 3 ALT, 1 PCFF, 1 FJF | PMMF | Oral cavity |
Oropharynx | |||||||||
de Bree, 2007 [20] | U | Retrospective review – Matched cohort | 19 | 80 | 40 | 40 | RFFF | PMMF | Oral cavity |
Oropharynx | |||||||||
Smeele, 2006 [29] | V | Retrospective – Matched cohort | 20 | 64 | 32 | 32 | N/A | PMMF | Oral cavity |
Oropharynx | |||||||||
Chien, 2005 [26] | W | Case series | 17 | 27 | 11 | 16 | RFFF | PBFPF | Oral cavity |
Chepeha, 2004 [8] | X | Retrospective review | 19 | 179 | 71 | 108 | N/A | PMMF | Oral cavity |
Oropharynx | |||||||||
Hypopharynx | |||||||||
Neck | |||||||||
Others | |||||||||
Funk, 2002 [19] | Y | Case-control, matched pairs study | 20 | 42 | 21 | 21 | FTT | N/A | Oral cavity |
Oropharynx | |||||||||
Hypopharynx | |||||||||
Larynx | |||||||||
Petruzzelli, 2002 [31] | Z | Retrospective review | 18 | 39 | 24 | 15 | FTT | N/A | N/A |
Amarante, 2000 [34] | Aa | Case-series | 6 | 117 | 49 | 68 | 23 RFFF, 3 ORFF, 2 CFF, 5 LDF, 5 RAFF, 3 MSA, 2 PSFF, 2 ICC, 1 GOM, 3 FJF | 47 PMMF, 7 PLDF, 2 PLTM, 9 TEMP, 3 MEC | Orbit |
Parotid | |||||||||
Skull base | |||||||||
Oropharynx | |||||||||
Larynx / hypopharynx | |||||||||
Mandibular | |||||||||
Neck | |||||||||
Tsue, 1997 [24] | Ab | Retrospective review | 19 | 53 | 29 | 24 | N/A | PMMF | Oral cavity |
Oropharynx | |||||||||
Kroll, 1997 [13] | Ac | Retrospective review | 17 | 178 | 145 | 33 | 89 RFFF, 56 RAFF | PMMF | Oral cavity |
Oropharynx | |||||||||
Kroll 1992 [33] | Ad | Retrospective review | 18 | 69 | 30 | 39 | RAFF | PMMF | N/A |