Skip to main content

Table 2 Demographic data, preoperative risk factors and ASA class

From: Free versus pedicled flaps for reconstruction of head and neck cancer defects: a systematic review

 

Total # of articles reporting

(total = n)

# of articles reporting differences

(total n)

Articles reporting differences

FF

PF

p-value

Age, mean ± SD

or mean (range)

16 B, D, H, K, L, M, N, O, P, R, T, W, X, Z, Aa, Ac

(n = 1855)

4

(n = 1067)

Goyal, 2017

64.0 ± 12.0

66.5 ± 12.9

0.017

Deganello, 2013

58.2 ± 6.32

69.6 ± 6.8

< 0.01

Fang, 2013

58.0 (25–78)

72.4 (55–80)

< 0.001

57.2 (46–72)

< 0.001

Kroll, 1997

56 ± 13

62 ± 12

0.0046

Age (median)

3 A, E, Ab

(n = 601)

1

(n = 517)

Sinha, 2017

65.9

(57.7–74.2)

67.9

(60.3–76.8)

0.037

Age > 50 years

4 C, F, I, J

(n = 293)

0

    

Male

20 A, D, C, F, E, H, I, J, K, L, M, N, O, P, R, T, W, X, Aa, Ab

(n = 1609)

2

(n = 151)

Li, 2016

17(70.83%)

17(100%)

0.043

Zhang X, 2014

66 (88%)

31 (32.0%)

0.018

Smoking

5 F, K, L, T, Y

(n = 300)

0

 

62.0%

61.8%

0.985

Prior head and neck surgery

4 B F X, Ab

(n = 1134)

2

(n = 902)

Goyal, 2017

189 (32.1%)

122 (58.7%)

< 0.001

Geiger, 2016a

14.0%

30.9%

0.039

Systemic diseases

(CVD, HTA, DM)

1 N

(n = 56)

1

(n = 56)

Fang, 2013

4 (20%)

20 (83.33%)

< 0.001

3 (25%)

< 0.001

COPD

2 A, T

(n = 587)

0

    

DM

3 A, L, P

(n = 651)

1

(n = 34)

Granzow, 2013

5 (31%)

0

0.02

HTA

2 F, L

(n = 139)

0

    

CAD

3 A, L, T

(n = 621)

0

    

DLP

1 F

(n = 105)

0

    

CHF

1 A

(n = 517)

0

    

aFIB

1 A

(n = 517)

1

(n = 517)

Sinha, 2017

7.0%

15.0%

0.0083

Alcoholism

1 T

(n = 70)

0

    

Other cancer

1 T

(n = 70)

0

    

ASA Class I-II, n (%)

6 B, L, R, T, U, Y

(n = 1043)

2

(n = 877)

Goyal, 2017

245 (41.6%)

56 (26.9%)

0.001

de Bree, 2007

32 (80%)

37 (92.5%)

0.028

ASA Class III-IV, n (%)

6 B, L, R, T, U, Y

(n = 1043)

2

(n = 877)

Goyal, 2017

343 (58.2%)

152 (73.1%)

0.001

de Bree, 2007

8 (20%)

3 (8%)

0.028

ASA mean factor

(mean ± SD)

4 A, H, R, Ac

(n = 736)

2

(n = 538)

Sinha, 2017

2.6 ± 0.03

2.8 ± 0.05

0.0007

Forner, 2016

2.3

2.4

0.05

  1. aFIB atrial fibrillation, ASA risk factor: scored using the American Society of Anesthesiology Scale (ASA), CAD Cardiac artery disease, CHF Chronic heart failure, COPD Chronic obstructive pulmonary disease, CVD Cardiovascular disease, DM Diabetes mellitus, DLP Dyslipidemia, HTA Hypertension