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Table 3 Staging and treatment data

From: Free versus pedicled flaps for reconstruction of head and neck cancer defects: a systematic review

 

Total # of articles

reporting

(total = n)

# of articles reporting differences

(total n)

Articles reporting difference

FF

PF

p-value

Prior radiation

11 B, D, E, F, K, L, O, T, X, Ab, Ac

(n = 1628)

2

(n = 850)

Goyal, 2017

272 (46.2%)

130 (62.5%)

< 0.001

Tsue, 1997

8 (28%)

13 (54%)

0.05

Prior chemotherapy

5 D, K, L, O, Ab

(n = 268)

0

    

T1

8 J, K, M, N, O, P, W, Y

(n = 480)

1

(n = 36)

Deganello, 2013

0

4 (20%)#

< 0.01

T2

8 J, K, M, N, O, P, W, Y

(n = 480)

1

(n = 36)

Deganello, 2013

7 (43.8%)#

5 (25%)#

< 0.01

T3

8 J, K, M, N, O, P, W, Y

(n = 480)

1

(n = 36)

Deganello, 2013

8 (50%)

8 (40%)

< 0.01

T4

8 J, K, M, N, O, P, W, Y

(n = 480)

1

(n = 36)

Deganello, 2013

1 (6.25%)

3 (15%)

< 0.01

T1-T2

4 C, H, T, Ab (n = 185)

0

    

T3-T4

4 C, H, T, Ab (n = 185)

0

    

Stage I-II

1 X (n = 179)

0

    

Stage III-IV

1 X (n = 179)

0

    

Surg + chemoradio

6 C, N, O, P, U

(n = 516)

1

(n = 60)

Paydarfar, 2011

16 (48.48%)#

12 (44.44%)#

0.03

Surg + radio

4 J, O, P, X (n = 449)

0

    

Tumor stage

1Ac (n = 178)

0

    

Tumor recurrence

1Ac (n = 178)

0

    
  1. Surg + chemoradio: Surgical resection and adjuvant chemoradiotherapy
  2. Surg + radio: Surgical resection and adjuvant radiotherapy
  3. # Percentage calculated relying on the data presented. Percentage not provided by the article
  4. Bold = Statistically significant, p-value ≤ 0.05