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Table 5 Post-operative complications and outcomes

From: Free versus pedicled flaps for reconstruction of head and neck cancer defects: a systematic review

 

Total # of articles reporting

(total = n)

# of articles reporting differences

(total n)

Articles reporting difference

FF

PF

p-value

Any complications

7 F, J, K, L, O, Aa, Ad

(n = 544)

3

(n = 284)

Geiger, 2016

68.0%

36.4%

0.001

Zhang X, 2014

13 (16.46%)

14 (45.16%)

0.002

Kroll, 1992

4 (13%)

17 (44%)

0.0145

Infection

3 F, L, T

(n = 209)

0

    

Recipient site infection

6 B, D, O, S, T, X

(n = 1292)

1

(n = 179)

Chepeha, 2004

2 (3%)

18 (17%)

< 0.004

Donor site infection

3 B, D, S

(n = 983)

0

    

Donor site morbidity

1 Q

(n = 202)

0

    

Fistula

11 B, F, K, O, Q, S, R, T, V, X, Aa

(n = 1777)

2

(n = 902)

Goyal, 2017

18 (3.1%)

17 (8.2%)

0.005

 

Geiger, 2016

22.0%

7.3%

0.039

Abscess

1 F

(n = 105)

0

    

Dehiscence recipient or donor site

4 F, K, S, V

(n = 332)

1

(n = 105)

Geiger, 2016

44.0%

23.6%

0.029

Dehiscence recipient site

5 D, L, O, V, X

(n = 409)

1

(n = 179)

Chepeha, 2004

0

11 (10%)

< 0.008

Dehiscence donor site

8 D, I, L, O, V, K, L, R (n = 370)

0

    

Hematoma

2 X, S

(n = 293)

0

    

Hematoma Donor site

2 E, V

(n = 95)

0

    

Hematoma recipient site

2 O, V

(n = 124)

0

    

Partial flap necrosis

6 I, O, V, X, Aa, Ad

(n = 526)

1

(n = 179)

Chepeha, 2004

2 (2.82%)#

12 (11%)#

< 0.006

Total flap necrosis

2 V, Aa

(n = 181)

0

    

Partial or total flap necrosis

1 T

(n = 70)

1

(n = 70)

Mallet, 2009

1 (4%)

14 (31%)

0.02

Osteonecrosis

2B, F

(n = 902)

1

(n = 105)

Geiger, 2016

24.0%

3.6%

0.007

Deep Vein Thrombosis (Inferious member)

2 A, S

(n = 631)

0

    

Venous obstruction (At site)

1 O

(n = 60)

0

    

Late anastomotic stricture

1Q

(n = 202)

0

    

Operative revision surgery

8 E, F, L, O, S, R, X, Aa (n = 660)

2 (n = 136)

Howard, 2016

1.6 (1–3)

0.6 (0–1)

< 0.00001

Geiger, 2016

34%

9.1%

0.003

Flap failure

8 E, I, K, L, O, T, U, V (n = 425)

1 (n = 70)

Mallet, 2009

1 (4%)

14 (31%)

0.02

Mortality at 30 days

2 (n = 228)K, X

     

Mortality at 1-year

2 (n = 76)L, Y

     

Mortality at 2-year

1 (n = 80)U

     
  1. # Percentage not provided by the original article, calculated by the authors from the data presented