From: Free versus pedicled flaps for reconstruction of head and neck cancer defects: a systematic review
 | Total # of articles reporting (total = n) | # of articles reporting differences (total n) | Articles reporting difference | FF | PF | p-value |
---|---|---|---|---|---|---|
Any complications | 7 F, J, K, L, O, Aa, Ad (n = 544) | 3 (n = 284) | Geiger, 2016 | 68.0% | 36.4% | 0.001 |
Zhang X, 2014 | 13 (16.46%) | 14 (45.16%) | 0.002 | |||
Kroll, 1992 | 4 (13%) | 17 (44%) | 0.0145 | |||
Infection | 3 F, L, T (n = 209) | 0 |  |  |  |  |
Recipient site infection | 6 B, D, O, S, T, X (n = 1292) | 1 (n = 179) | Chepeha, 2004 | 2 (3%) | 18 (17%) | < 0.004 |
Donor site infection | 3 B, D, S (n = 983) | 0 |  |  |  |  |
Donor site morbidity | 1 Q (n = 202) | 0 |  |  |  |  |
Fistula | 11 B, F, K, O, Q, S, R, T, V, X, Aa (n = 1777) | 2 (n = 902) | Goyal, 2017 | 18 (3.1%) | 17 (8.2%) | 0.005 |
 | Geiger, 2016 | 22.0% | 7.3% | 0.039 | ||
Abscess | 1 F (n = 105) | 0 |  |  |  |  |
Dehiscence recipient or donor site | 4 F, K, S, V (n = 332) | 1 (n = 105) | Geiger, 2016 | 44.0% | 23.6% | 0.029 |
Dehiscence recipient site | 5 D, L, O, V, X (n = 409) | 1 (n = 179) | Chepeha, 2004 | 0 | 11 (10%) | < 0.008 |
Dehiscence donor site | 8 D, I, L, O, V, K, L, R (n = 370) | 0 |  |  |  |  |
Hematoma | 2 X, S (n = 293) | 0 |  |  |  |  |
Hematoma Donor site | 2 E, V (n = 95) | 0 |  |  |  |  |
Hematoma recipient site | 2 O, V (n = 124) | 0 |  |  |  |  |
Partial flap necrosis | 6 I, O, V, X, Aa, Ad (n = 526) | 1 (n = 179) | Chepeha, 2004 | 2 (2.82%)# | 12 (11%)# | < 0.006 |
Total flap necrosis | 2 V, Aa (n = 181) | 0 |  |  |  |  |
Partial or total flap necrosis | 1 T (n = 70) | 1 (n = 70) | Mallet, 2009 | 1 (4%) | 14 (31%) | 0.02 |
Osteonecrosis | 2B, F (n = 902) | 1 (n = 105) | Geiger, 2016 | 24.0% | 3.6% | 0.007 |
Deep Vein Thrombosis (Inferious member) | 2 A, S (n = 631) | 0 |  |  |  |  |
Venous obstruction (At site) | 1 O (n = 60) | 0 |  |  |  |  |
Late anastomotic stricture | 1Q (n = 202) | 0 |  |  |  |  |
Operative revision surgery | 8 E, F, L, O, S, R, X, Aa (n = 660) | 2 (n = 136) | Howard, 2016 | 1.6 (1–3) | 0.6 (0–1) | < 0.00001 |
Geiger, 2016 | 34% | 9.1% | 0.003 | |||
Flap failure | 8 E, I, K, L, O, T, U, V (n = 425) | 1 (n = 70) | Mallet, 2009 | 1 (4%) | 14 (31%) | 0.02 |
Mortality at 30 days | 2 (n = 228)K, X |  |  |  |  |  |
Mortality at 1-year | 2 (n = 76)L, Y |  |  |  |  |  |
Mortality at 2-year | 1 (n = 80)U |  |  |  |  |  |