Table 6 Quality of Life data
From: Free versus pedicled flaps for reconstruction of head and neck cancer defects: a systematic review
| Â | Article | FF | PF | p-value | |
|---|---|---|---|---|---|
UW-QOL Global | Li, 2016# | 55.14 ± 9.24 | 54.36 ± 8.13 | 0.965 | |
Zhang X, 2014$ | 70.5 ± 16.7 | 67.3 ± 12.9 | 0.860 | ||
Hsing, 2011& | 66.0 ± 18.5 | 57.8 ± 18.2 | 0.090 | ||
UW-QOL: Pain | Li, 2016 | 71.63 ± 9.91 | 72.94 ± 11.13 | 0.751 | |
Zhang X, 2014 | 86.2 ± 10.8 | 89.9 ± 11.4 | 0.425 | ||
Hsing, 2011 | 76.8 ± 23.0 | 68.1 ± 27.2 | 0.138 | ||
UW-QOL: Swallowing | Li, 2016 | 44.00 ± 16.27 | 43.78 ± 4.95 | 0.741 | |
Zhang X, 2014 | 49.4 ± 14.7 | 51.3 ± 21.7 | 0.840 | ||
Hsing, 2011 | 49.3 ± 37.2 | 48.6 ± 32.7 | 0.962 | ||
UW-QOL: Chewing | Li, 2016 | 42.45 ± 6.15 | 43.43 ± 12.37 | 0.817 | |
Zhang X, 2014 | 52.6 ± 17.1 | 59.4 ± 12.9 | 0.498 | ||
Hsing, 2011 | 34.5 ± 39.0 | 33.6 ± 36.7 | 0.973 | ||
UW-QOL: Speech | Li, 2016 | 51.27 ± 11.24 | 52.63 ± 12.43 | 0.461 | |
Zhang X, 2014 | 57.5 ± 20.1 | 76.1 ± 13.3 | 0.017 | ||
Hsing, 2011 | 66.7 ± 27.2 | 44.7 ± 35.0 | 0.002 | ||
UW-QOL: Apparence | Li, 2016 | 57.47 ± 11.44 | 68.54 ± 13.24 | 0.0001 | |
Zhang X, 2014 | 76.4 ± 18.6 | 70.3 ± 17.1 | 0.308 | ||
Hsing, 2011 | 67.3 ± 25.0 | 69.8 ± 25.5 | 0.535 | ||
UW-QOL: Activity | Li, 2016 | 64.23 ± 9.52 | 63.73 ± 8.41 | 0.641 | |
Zhang X, 2014 | 71.9 ± 11.5 | 74.8 ± 10.2 | 0.710 | ||
Hsing, 2011 | 67.9 ± 24.2 | 66.8 ± 27.9 | 0.760 | ||
UW-QOL: Recreation | Li, 2016 | 66.59 ± 11.62 | 67.26 ± 9.23 | 0.445 | |
Zhang X, 2014 | 72.1 ± 10.2 | 78.9 ± 11.2 | 0.590 | ||
Hsing, 2011 | 69.1 ± 32.6 | 62.5 ± 32.2 | 0.221 | ||
UW-QOL: Shoulder | Li, 2016 | 61.52 ± 7.83 | 54.65 ± 11.24 | 0.0001 | |
Zhang X, 2014 | 87.1 ± 14.4 | 65.6 ± 20.0 | < 0.001 | ||
Hsing, 2011 | 81.4 ± 14.7 | 50.5 ± 29.8 | < 0.001 | ||
UW-QOL: Taste | Li, 2016 | 50.91 ± 10.64 | 51.24 ± 11.23 | 0.673 | |
Zhang X, 2014 | 48.4 (18.3) | 52.9 (19.6) | 0.713 | ||
Hsing, 2011 | 55.0 ± 43.2 | 45.9 ± 39.6 | 0.226 | ||
UW-QOL: Salive | Li, 2016 | 45.48 ± 16.92 | 44.17 ± 12.78 | 0.723 | |
Zhang X, 2014 | 70.9 ± 9.5 | 72.3 ± 23.1 | 0.813 | ||
Hsing, 2011 | 71.7 ± 34.8 | 73.8 ± 28.1 | 0.964 | ||
UW-QOL: Mood | Li, 2016 | 69.94 ± 9.51 | 68.31 ± 14.72 | 0.474 | |
Zhang X, 2014 | 76.0 ± 14.7 | 71.6 ± 18.8 | 0.114 | ||
Hsing, 2011 | 76.2 ± 24.7 | 60.8 ± 32.8 | 0.022 | ||
UW-QOL: Anxiety | Li, 2016 | 70.57 ± 15.11 | 72.55 ± 15.19 | 0.219 | |
Zhang X, 2014 | 78.5 ± 9.64 | 86.4 ± 17.5 | 0.775 | ||
Hsing, 2011 | 75.9 ± 26.3 | 68.9 ± 33.9 | 0.423 | ||
UW-QOL: Composite score | Hsing, 2011 | 66.0 ± 18.5 | 57.8 ± 18.2 | 0.090 | |
Speech | Excellent | Zhang S, 2015§ | 12 (80.0%)# | 11 (91.7%)# | 0.62 |
Good | 3 (20%) | 1 (8.3%) | |||
Poor | 0 | 0 | |||
Always understandable | O’Neil, 201 | 17 (53.1) | 4 (22.2) | 0.014 | |
Usually understandable | 14 (43.8) | 9 (50.0) | |||
Difficult to understand | 1 (3.1) | 5 (27.8) | |||
Swallowing full/regular diet at follow-up (vs soft, liquid) n (%) | Zhang S, 2015§ | 13 (86.7%)# | 10 (83.3%)# | 1.00 | |
Paydarfar, 2011% | 19 | 20 | 0.60 | ||
Chan Y, 2011* | 8 (38.2%) | 24 (35.8%) | ND | ||
52 (61.9%) | ND | ||||
O’Neil, 2010** | 17 (59.4%) | 6 (33.3%) | 0.202 | ||
Tsue, 1997*** | 8 (34%) | 4 (17%) | 0.02 | ||
Preoperative mouth-open width distance (mean) cm | Fang, 2013 | 1.5–6.2 (4.6) | 1.2–6.2 (4.8) | ND | |
0.9–6.0 (3.5) | ND | ||||
Chien, 2005 | 6.3–3.5 (5.7) | 6.1–2.5 (5.1) | 0.384 | ||
Postoperative mouth-open width | Fang, 2013 | 1.4–5.8 (4.3) | 1.1–4.7 (3.2) | ND | |
0.8–5.8 (3.3) | ND | ||||
Chien, 2005 | 5.9–3.2 (5.2) | 5.6–1.6 (3.6) | 0.384 | ||
Mouth-open width change (%) | Fang, 2013 | 4.0–9.1% | 8.3–47.5% | < 0.001 | |
3.3–11.1% | <0.001 | ||||
Chien, 2005 | 4.8–9.8% | 5–45.5% | < 0.001 | ||
G-tube at 6 months postoperatively | Smeele, 2006 | 21.8% | 34.3% | NS | |
G-tube dependence, n (%) | Chepeha, 2004 | 10 (16%) | 40 (42%) | 0.001 | |
Feeding tube for >21 days | Mallet, 2009 | 8 (36%) | 17 (42%) | 0.84 | |
Feeding tube at discharge | Tsue, 1997 | 20 (69%) | 20 (83%) | NS | |
Feeding tube at follow upe | 11 (39%) | 17 (85%) | 0.002 | ||