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Table 1 Clinicopathological characteristics of the study population

From: Prevalence and aggressiveness of papillary thyroid carcinoma in surgically-treated graves’ disease patients: a retrospective matched cohort study

Variables

GD Group

Control Group

p-value

Age (years)

46 ± 14 (16–78)

46 ± 14 (19–75)

0.236

Gender

 Female

54 (82%)

54 (82%)

1.000

 Male

12 (18%)

12 (18%)

1.000

MNTS

4.92 ± 4.6

8.63 ± 5.7

*0.03

Bethesda Category

2.70 ± 1.5

3.82 ± 1.5

*0.04

Nodule status

 Without nodule

15 (23%)

17 (26%)

0.788

 With nodule

  Solitary nodule

18 (27%)

26 (39%)

0.286

  Multinodular

33 (50%)

23 (35%)

 

 Nodule (cm)

2.1 ± 1.3 (0.4–6.0)

2.2 ± 1.2 (0.5–5.5)

0.524

Pathology

 Benign

30 (45%)

35 (53%)

0.385

 If malignant

36 (55%)

31 (47%)

 

  Incidental carcinoma

20 (31%)

9 (14%)

*0.04

  Papillary carcinoma

7 (11%)

9 (13%)

0.06

  Aggressive

9 (13%)

13 (20%)

0.55

Mean tumor size (cm)

2.3 ± 1.3

1.8 ± 0.5

*0.05

Lymph node metastasis

8 (12%)

6 (9%)

0.599

Extrathyroidal extension

4 (6%)

5 (7.5%)

1.00

Invasion

 Lymphatic

4 (6%)

0 (0%)

N/ANéA

 Vascular

0 (0%)

0 (0%)

N/A

Radioactive iodine therapy

 Yes

9 (14%)

9 (14%)

1.000

 No

57 (86%)

57 (86%)

Recurrence

 Yes

0 (0%)

0 (0%)

1.000

 No

66 (100%)

66 (100%)

Survival on latest follow-up

 Yes

65 (98%)

66 (100%)

1.000

 No

1 (2%)

0 (0%)

  1. Data are presented as mean ± SD (range) or mean (percentage)
  2. FNA = fine needle aspiration; MNTS = McGill Nodule Thyroid Score
  3. *p < 0.05