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Table 1 Clinicopathological characteristics of the study population

From: Prevalence and aggressiveness of papillary thyroid carcinoma in surgically-treated graves’ disease patients: a retrospective matched cohort study

Variables GD Group Control Group p-value
Age (years) 46 ± 14 (16–78) 46 ± 14 (19–75) 0.236
Gender
 Female 54 (82%) 54 (82%) 1.000
 Male 12 (18%) 12 (18%) 1.000
MNTS 4.92 ± 4.6 8.63 ± 5.7 *0.03
Bethesda Category 2.70 ± 1.5 3.82 ± 1.5 *0.04
Nodule status
 Without nodule 15 (23%) 17 (26%) 0.788
 With nodule
  Solitary nodule 18 (27%) 26 (39%) 0.286
  Multinodular 33 (50%) 23 (35%)  
 Nodule (cm) 2.1 ± 1.3 (0.4–6.0) 2.2 ± 1.2 (0.5–5.5) 0.524
Pathology
 Benign 30 (45%) 35 (53%) 0.385
 If malignant 36 (55%) 31 (47%)  
  Incidental carcinoma 20 (31%) 9 (14%) *0.04
  Papillary carcinoma 7 (11%) 9 (13%) 0.06
  Aggressive 9 (13%) 13 (20%) 0.55
Mean tumor size (cm) 2.3 ± 1.3 1.8 ± 0.5 *0.05
Lymph node metastasis 8 (12%) 6 (9%) 0.599
Extrathyroidal extension 4 (6%) 5 (7.5%) 1.00
Invasion
 Lymphatic 4 (6%) 0 (0%) N/ANéA
 Vascular 0 (0%) 0 (0%) N/A
Radioactive iodine therapy
 Yes 9 (14%) 9 (14%) 1.000
 No 57 (86%) 57 (86%)
Recurrence
 Yes 0 (0%) 0 (0%) 1.000
 No 66 (100%) 66 (100%)
Survival on latest follow-up
 Yes 65 (98%) 66 (100%) 1.000
 No 1 (2%) 0 (0%)
  1. Data are presented as mean ± SD (range) or mean (percentage)
  2. FNA = fine needle aspiration; MNTS = McGill Nodule Thyroid Score
  3. *p < 0.05