Fig. 4
From: Molecular mutations as a possible factor for determining extent of thyroid surgery
Photomicrographs from a case of PTC, tall cell variant. In this case, tall cell features (i.e. tumour cells 2 or 3 times taller than wide) were present both on the FNA material a and b, Cell block, H&E), which was classified as Malignant-PTC (Bethesda VI), and on the corresponding resection specimen (c and d, H&E). The tumour cells also show classical nuclear features of PTC including several intranuclear pseudoinclusions (arrows in A). Extrathyroidal extension was present (D, H&E) with several clusters of tumour cells (arrows) invading skeletal muscle. Molecular testing revealed BRAF V600E mutation