Table 1 Demographics of the participants
Male | Female | Total | |
|---|---|---|---|
Number | 400 (56.1%) | 313 (43.9%) | 713 (100%) |
Age (Years) | 72.42 ± 6.14 | 71.56 ± 5.71 | 72.04 ± 5.96 |
Bilateral PTA average (dBHL) | 67.96 ± 18.87 | 55.27 ± 18.93 | 62.36 ± 19.92 |
Occupational noise exposure | 178 (44.5%) | 54 (17.3%) | 232 (32.5%) |
ARHI grouping | |||
ARHI susceptible | 142 (35.5%) | 40 (12.8%) | 182 (25.5%) |
Intermediate | 197 (49.2%) | 158 (50.5%) | 355 (49.8%) |
ARHI resistant | 61 (15.2%) | 115 (36.7%) | 176 (24.7%) |
Genotype | |||
IL1R1 | |||
rs3917225 | |||
AA | 130 (32.5%) | 112 (35.8%) | 242 (33.9%) |
AG | 188 (47.0%) | 137 (43.8%) | 325 (45.6%) |
GG | 60 (15.0%) | 46 (14.7%) | 106 (14.9%) |
Undetermined | 22 (5.5%) | 18 (5.8%) | 40 (5.6%) |
rs2234650 | |||
CC | 225 (56.2%) | 146 (46.6%) | 371 (52.0%) |
CT | 141 (35.2%) | 136 (43.5%) | 277 (38.8%) |
TT | 25 (6.2%) | 20 (6.4%) | 45 (6.3%) |
Undetermined | 9 (2.8%) | 11 (3.5%) | 20 (2.8%) |
IL1R2 | |||
rs4141134 | |||
TT | 356 (89.0%) | 277 (88.5%) | 633 (88.8%) |
TC | 32 (8.0%) | 21 (6.7%) | 53 (7.4%) |
CC | 0 (0) | 0 (0) | 0 (0) |
Undetermined | 12 (3.0%) | 15 (4.8%) | 27 (3.8%) |
rs2071008 | |||
GG | 223 (55.8%) | 188 (60.1%) | 411 (57.6%) |
GT | 138 (34.5%) | 99 (31.6%) | 237 (33.2%) |
TT | 16 (4.0%) | 13 (4.2%) | 29 (4.1%) |
Undetermined | 23 (5.8%) | 13 (4.2%) | 36 (5.0%) |
Allele | |||
IL1R1 | |||
rs3917225 | |||
A | 448 (59.3%) | 361 (61.2%) | 809 (60.1%) |
G | 308 (40.7%) | 229 (38.8%) | 537 (39.9%) |
rs2234650 | |||
C | 591 (75.6%) | 428 (70.9%) | 1019 (73.5%) |
T | 191 (24.4%) | 176 (29.1%) | 367 (26.5%) |
IL1R2 | |||
rs4141134 | |||
T | 744 (95.9%) | 575 (96.5%) | 1319 (96.1%) |
C | 32 (4.1%) | 21 (3.5%) | 53 (3.9%) |
rs2071008 | |||
G | 584 (77.5%) | 475 (79.2%) | 1059 (78.2%) |
T | 170 (22.5%) | 125 (20.8%) | 295 (21.8%) |