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Table 2 Relationships between alleles of IL-1 receptor genetic polymorphisms and age-related hearing impairment

From: The association of genetic polymorphisms in interleukin-1 receptors type 1 and type 2 with age-related hearing impairment in a Taiwanese population: a case control study

GeneSNPsAlleleARHIControlCrudeAdjusteda
OR (95% CI)POR (95% CI)p
IL1R1rs3917225A216 (63.2%)186 (57.1%)1.000 1.000 
  G126 (36.8%)140 ((42.9%)0.775 (0.568–1.057)0.1070.587 (0.383–0.901)0.015*
 rs2234650C270 (75.4%)225 (71.7%)1.000 1.000 
  T88 (24.6%)89 (28.3%)0.934 (0.664–1.313)0.6941.028 (0.654–1.616)0.905
IL1R2rs4141134T343 (96.3%)333 (96.2%)1.000 1.000 
  C13 (3.7%)13 (3.8%)0.971 (0.444–2.125)0.9410.595 (0.209–1.699)0.332
 rs2071008G276 (78.4%)261 (79.6%)1.000 1.000 
  T76 (21.6%)67 (20.4%)1.073 (0.741–1.552)0.7101.062 (0.641–1.760)0.816
  1. a: Logistic regression; adjusted for age, sex and noise exposure
  2. *: p < 0.05