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Table 2 Relationships between alleles of IL-1 receptor genetic polymorphisms and age-related hearing impairment

From: The association of genetic polymorphisms in interleukin-1 receptors type 1 and type 2 with age-related hearing impairment in a Taiwanese population: a case control study

Gene

SNPs

Allele

ARHI

Control

Crude

Adjusteda

OR (95% CI)

P

OR (95% CI)

p

IL1R1

rs3917225

A

216 (63.2%)

186 (57.1%)

1.000

 

1.000

 
  

G

126 (36.8%)

140 ((42.9%)

0.775 (0.568–1.057)

0.107

0.587 (0.383–0.901)

0.015*

 

rs2234650

C

270 (75.4%)

225 (71.7%)

1.000

 

1.000

 
  

T

88 (24.6%)

89 (28.3%)

0.934 (0.664–1.313)

0.694

1.028 (0.654–1.616)

0.905

IL1R2

rs4141134

T

343 (96.3%)

333 (96.2%)

1.000

 

1.000

 
  

C

13 (3.7%)

13 (3.8%)

0.971 (0.444–2.125)

0.941

0.595 (0.209–1.699)

0.332

 

rs2071008

G

276 (78.4%)

261 (79.6%)

1.000

 

1.000

 
  

T

76 (21.6%)

67 (20.4%)

1.073 (0.741–1.552)

0.710

1.062 (0.641–1.760)

0.816

  1. a: Logistic regression; adjusted for age, sex and noise exposure
  2. *: p < 0.05