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Table 1 Patient characteristics according to p16 status (n = 81 patients)

From: Factors influencing patient and health care delays in Oropharyngeal Cancer

 

p16-positive, n = 64 (%)

p16-negative, n = 17 (%)

P value

All, n = 83 (%)

Sex

 Male

46 (71.9)

12 (70.6)

1.000

60 (72.3)

 Female

18 (28.1)

5 (29.4)

 

23 (27.7)

Mean age (in years)

59.7

66.6

0.023

61.4

History of smoking

 Never smoked

23 (35.9)

2 (11.8)

< 0.001

26 (31.3)

 Former smoker

33 (51.6)

5 (29.4)

 

39 (47.0)

 Current smoker

8 (12.5)

10 (58.8)

 

18 (21.7)

Excessive use of alcohol

 No

46 (71.9)

4 (23.5)

< 0.001

52 (62.6)

 Yes

11 (17.2)

6 (35.3)

 

17 (20.5)

 Previous use

7 (10.9)

7 (41.2)

 

14 (16.9)

T classb

 T1–2

47 (73.4)

13 (76.5)

1.000

61 (73.5)

 T3–4

17 (26.6)

4 (23.5)

 

22 (26.5)

N classb

 N+

10 (15.6)

6 (35.3)

0.090

16 (19.3)

 N0

54 (84.4)

11 (64.7)

 

67 (80.7)

Stageb

 I-II

6 (9.4)

5 (29.4)

0.047

11 (13.3)

 III-IV

58 (90.6)

12 (70.6)

 

72 (86.7)

Histological gradec

 I

1 (1.6)

2 (12.5)

0.005

3 (3.7)

 II

9 (14.3)

6 (37.5)

 

16 (19.8)

 III

53 (84.1)

8 (50.0)

 

62 (76.5)

  1. aIn 2 patients, p16 staining was unavailable
  2. bAccording to UICC, 7th edition
  3. cn = 81; p16-positive (n = 63), p16-negative (n = 16)