|Study authors||Year||Study design||Level of evidence||Study groups||Intervention||Outcome||Conclusion|
|Jeon et al. ||2009||Diagnostic study||B||8 IP patients, 6 of them with IP associated SCC.||SUVs of PET/CT images and CCP of MR images are reviewed and compared. SCC are confirmed by histologic exam.||In PET/CT study, IP with SCC has consistently higher SUVs than IPs without SCC; however this test has low specificity. MRI findings showed wide discrepancy in terms of CCP distribution. Aggressive bone destruction was found in most SCC patients.||PET/CT cannot be used reliably to predict malignancy yet due to limited data.|
Focal loss of CCP on MR might not be additional sign of malignancy.
|Allegra et al. ||2012||Diagnostic study||B||12 cases (7 IP)||18 FDG - PET/CT of IP patients were analyzed and compared with histological results.||For IP patients the SUVmax value is larger than for non IP patients.||Lesions with a negative or diffuse 18FDG uptake with SUVmax less than 3 should be considered negative for IP.|
|Shojaku et al. ||2007||Observational study||C||5 IP patients, 2 of them have IP associated SCC||FDG PET was performed on IP patients and SUVmax was analyzed.||High FDG uptake (SUVmax) was observed in all patients, with a higher SUVmax in SCC patients.||The SUVmax of IP can warn the physician of the probability of an associated malignancy.|
|Yilmaz et al. ||2015||Observational study||C||8 nasal polyps vs 10 IP vs 9 SCC||PET CT of 27 patients were analyzed.||The mean SUVmax was found to be high in the IP group, and highest in the SCC group.||High SUVmax can be used to rule out nasal polyp. The SCC group had a higher SUVmax.|
|Zhang et al. ||2015||Case report||D||1 IP patient||SIP with co-existent malignancy and cervical metastasis was reviewed.||PET failed to identify the primary malignancy site because there was no SUV increase in SCC.||FDG PET/CT may be not a reliable predictor of malignancy in SIP.|
|Kim et al. ||2017||Case report||D||1 IP patient||Patient had two operations and 2 sequential PET CT scans.||N/A||The SUV of IP could vary over time in PET CT. PET CT is not an ideal tool to distinguish IP from other inflammatory polyps or cancer.|