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Table 6 Characteristics of included studies on tracheotomies

From: Clinical evidence based review and recommendations of aerosol generating medical procedures in otolaryngology – head and neck surgery during the COVID-19 pandemic

Author, yearStudy DesignLevel of EvidenceSubjects (n)Study GroupsStudy outcomesConclusionDirectness of evidence
Chen, 2009 [29]Retrospective cohort study3758HCWs involved in care of SARS patientsRisk factors for SARS infection in HCWs, based on survey.Univariate regression reveals increased OR for developing SARS: 4.15 (1.50–11.50), but this was not significant in their multivariate log regression analysis, which did not reveal an increased risk of performing tracheotomy.Indirect
Wei, 2003 [30]Cohort study, with high risk of bias43HCWs involved in SARS patients, requiring tracheotomiesSARS infection in HCWs, 3 tracheotomiesNo medical personnel became infected after carrying out the procedure.Indirect
Chee, 2004 [31]Case control4124 HCWsHCWs involved in care of SARS patientsSARS infection in HCWs. 41 surgical procedures, including 15 tracheotomiesNo transmission of SARS was reported within the operating roomIndirect
Tien, 2005 [32]Cohort study, with high risk of bias43HCWs involved in care of SARS patientsSARS infection in HCWs, 3 tracheotomiesSix months after the procedure, all staff involved in the tracheotomies remained healthyIndirect
  1. HCWs health care workers
  2. SARS severe acute respiratory syndrome
  3. OR odds ratio