Table 1 Patient Characteristics
Characteristic | Number of cases (%) | *p-value | ||
|---|---|---|---|---|
Baseline (2005–2009) n = 48 | Early pathway (2011–2012) n = 53 | Current pathway (2012–2018) n = 333 | ||
Gender | ||||
Male | 32 (67%) | 35 (66%) | 233 (70%) | ns |
Female | 16 (33%) | 18 (34%) | 100 (30%) | |
Age (yrs) | ||||
Mean (SD) | 63.5 (13.2) | 62.2 (12.1) | 61.7 (12.2) | ns |
Range | 22.9–84.9 | 32.8–88.0 | 21.2–89.0 | |
Alcohol consumption | ns | |||
Never Drinker | 11 (23%) | 8 (15%) | 68 (20%) | |
Ex Drinker | 4 (8%) | 4 (8%) | 81 (24%) | |
Current Drinker | 25 (52%) | 36 (68%) | 40 (12%) | |
Not Reported | 8 (17%) | 5 (9%) | 51 (15%) | |
Smoking status | ns | |||
Never Smoked | 17 (35%) | 15 (28%) | 83 (25%) | |
Ex Smoker | 15 (31%) | 17 (32%) | 108 (32%) | |
Current Smoker | 12 (25%) | 18 (34%) | 100 (30%) | |
Not Reported | 4 (8%) | 3 (6%) | 42 (13%) | |
Comorbidities | ns | |||
Diabetes | 3 (6%) | 5 (9%) | 43 (13%) | |
COPD | 9 (19%) | 12 (23%) | 41 (12%) | |
Hypertension | 23 (48%) | 23 (43%) | 139 (42%) | |
Heart Disease | 11 (23%) | – | 52 (16%) | |
Primary site | ns | |||
Oral Cavity | 40 (83%) | 42 (79%) | 222 (67%) | |
Skin | 1 (2%) | 1 (2%) | 31 (9%) | |
Paranasal Sinus | 2 (4%) | 2 (4%) | 22 (7%) | |
Other Site | 5 (10%) | 8 (15%) | 58 (17%) | |
Histology | 0.003* | |||
Squamous Cell | 44 (92%) | 48 (91%) | 264 (80%) | |
Other Cancer | 4 (8%) | 2 (4%) | 52 (16%) | |
Benign | 0 (0%) | 1 (2%) | 17 (5%) | |
Not Reported | 0 (0%) | 2 (4%) | 0 (0%) | |
Clinical stage | ns | |||
0 | 1 (2%) | 3 (6%) | 8 (2%) | |
I | 1 (2%) | 6 (11%) | 29 (9%) | |
II | 5 (10%) | 6 (11%) | 47 (14%) | |
III | 8 (17%) | 9 (17%) | 36 (11%) | |
IV | 25 (52%) | 24 (45%) | 163 (49%) | |
Not Stated | 8 (17%) | 5 (9%) | 50 (15%) | |
Number of free flaps | ns | |||
1 | 46 (96%) | 53 (100%) | 313 (94%) | |
2 | 2 (4%) | 0 (0%) | 20 (6%) | |