Table 1 Descriptive diagnosis of acute exacerbations in adult patients with CRS
Author/year | Definition of an acute exacerbation in CRS |
|---|---|
Zemke, et al. (2019) [13] | The presence of increased nasal congestion, and facial pain; increased sinonasal discharge; usually presence of an unscheduled sick visit. |
Orlandi, RR, et al. (2018) [8] | AE in CRS is defined in a patient in whom a previous diagnosis of CRS exists, and a sudden worsening of symptoms occurs, with a return to baseline symptoms following treatment. |
Divekar, et al. (2015) [14] | A natural exacerbation was defined as patient-reported worsening of sinonasal symptoms (i.e. runny nose, nasal congestion, and nasal obstruction). |
Fokkens, et al. (2012) [7] | A history of sudden worsening of preexisting symptoms suggests an acute exacerbation of chronic rhinosinusitis, which should be diagnosed by similar criteria and treated in a similar way to ARS. |
Kuiper, et al. (2018) [15] | Self-reported medication use (antibiotics and oral corticosteroids) for worsened nasal and sinus symptoms; self-reported worsened purulence in the past 4 weeks. |
Rank, et al. (2010) [16] | Systemic antibiotics; systemic corticosteroid; plans for a semi-urgent surgical intervention; emergency department or urgent care visit, or a hospitalization for CRS. |
Reh, et al. (2009) [17] | Worse nasal symptoms |