From: Prehabilitation in head and neck cancer patients: a literature review
First Author | Year | Study Type | Comparator Group | Sample Size by Allocation Group | Baseline Measures of Functional Outcomes | Overall Functional Outcomes |
---|---|---|---|---|---|---|
Ahlberg | 2011 [14] | Nonselective, longitudinal, prospective cohort study | Alternate RT center | Experimental n=190 Control n=184 | Yes | Negative Equivalent |
Ajmani | 2018 [38] | Retrospective cohort study | Patients seen prior to initiation of swallowing rehabilitation program | Experimental n=119 Control n=135 | Yes | Positive |
Baudelet | 2020 [32] | Study protocol for a randomized controlled trial | Service delivery method | Proposed 1:1:1 recruitment App supported n=50 Therapist supported n=50 Patient directed n=50 | Yes | N/A |
Carmignani | 2018 [30] | Part 1: retrospective Part 2: prospective two-arm case–control analysis | Usual care | Experimental n=6 Control n=6 | Yes | Positive |
Carnaby-Mann | 2012 [15] | Randomized Control Trial | Sham exercises Usual care | Experimental n=20 Sham n=18 Usual Care n=20 | Yes | Positive Equivalent |
Carroll | 2008 [35] | Retrospective case control | Post cancer treatment exercise only | Experimental n=9 Control n=9 | No | Positive Equivalent |
Cnossen | 2014 [22] | Feasibility study | Mode of program delivery | Leaflet n=11 Booklet + DVD n=11 Online n=11 | No | N/A |
Cnossen | 2017 [24] | Prospective clinical cohort study | None | n=50 | Yes | N/A |
Duarte | 2013 [36] | Case series with chart review | Noncompliant group | Experimental n=57 Control n=28 | Yes | Positive Equivalent |
Govender | 2020 [33] | Two-arm parallel group non-blinded randomized feasibility trial | Usual care | Experimental n=16 Control n=16 | Yes | N/A |
Guillen-Sola | 2019 [26] | Protocol for a single-blind randomized clinical trial | Late intervention (immediately after CRT completion) | Proposed 1:1 recruitment | Yes | N/A |
Hajdu | 2019 [27] | Randomized Control Trial | None (reports on adherence within the experimental group of a randomized control trial) | n=45 | N/A | N/A |
Hutcheson | 2013 [42] | Retrospective observational study | Non-adherent group | Experimental n=286 Control n=211 | No | Positive |
Kotz | 2012 [16] | Randomized controlled trial | Usual care | Experimental n=13 Control n=13 | Yes | Positive |
Kraaijenga | 2015 [23] | Randomized controlled trial | Repeated Measures | Baseline n=55 2 year n=29 6 year n=22 | Yes | Positive |
Kulbersh | 2006 [17] | Prospective cohort study and cross-sectional QOL analysis | Post treatment exercise (first visit after the initiation of their treatment). | Experimental n=25 Control n=12 | No | Positive Equivalent |
Mashhour | 2018 [28] | Comparative study | Not defined | Experimental n=30 Control n=30 | Yes | Positive Equivalent |
Messing | 2017 [25] | Randomized controlled trial | Usual care | Experimental n=30 Control n=30 | Yes | Positive Equivalent |
Mortensen | 2015 [18] | Randomized controlled trial | Usual care | Experimental n=22 Control n=22 | Yes | Equivalent with positive trends |
Ohba | 2016 [37] | Retrospective case-control design | Exercise provided when dysphagia developed | Experimental n=21 Control n=30 | Yes | Positive |
Peng | 2015 [40] | Retrospective case series | Prior to initiation of Swallowing Preservation Protocol (SPP) and those not enrolled once SPP was initiated | Experimental n=41 Control n=66 | Yes | Positive |
Retel | 2011 [41] | Retrospective cost-effectiveness analysis | Usual Care | Experimental n=37 Control n=53 | No | Positive |
Shinn | 2013 [39] | Retrospective | None | n=109 | No | N/A |
Starmer | 2018 [34] | Feasibility trial | None | n=36 | No | N/A |
Tang | 2011 [19] | Randomized controlled trial | Usual Care | Experimental n=22 Control n=21 | Yes | Positive |
van der Molen | 2011 [20] | Randomized controlled trial | Usual Care | Experimental n=27 Control n=22 | Yes | Positive |
Virani | 2015 [21] | Prospective alternate assignment and characteristic matching | Repetitive swallows | Experimental n=26 Control n=24 | Yes | Positive Equivalent |
Wall | 2020 [31] | Three-arm prospective stratified parallel group study with 1:1:1 random allocation. | Repeated Measures Service delivery mode | Technology n=25 Clinician directed n=25 Patient directed n=27 | Yes | N/A |
Wells | 2016 [29] | Feasibility study using quantitative and qualitative research methods within a quasi-experimental design | Usual Care | Proposed: Experimental n=40 Control n=30 | Yes | N/A |