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Table 1 Summary of included articles

From: Prehabilitation in head and neck cancer patients: a literature review

First Author Year Study Type Comparator Group Sample Size by Allocation Group Baseline Measures of Functional Outcomes Overall Functional Outcomes
Ahlberg 2011 [14] Nonselective, longitudinal, prospective cohort study Alternate RT center Experimental n=190
Control n=184
Yes Negative
Equivalent
Ajmani 2018 [38] Retrospective cohort study Patients seen prior to initiation of swallowing rehabilitation program Experimental n=119
Control n=135
Yes Positive
Baudelet 2020 [32] Study protocol for a randomized controlled trial Service delivery method Proposed 1:1:1 recruitment
App supported n=50
Therapist supported n=50
Patient directed n=50
Yes N/A
Carmignani 2018 [30] Part 1: retrospective
Part 2: prospective two-arm case–control analysis
Usual care Experimental n=6
Control n=6
Yes Positive
Carnaby-Mann 2012 [15] Randomized Control Trial Sham exercises
Usual care
Experimental n=20
Sham n=18
Usual Care n=20
Yes Positive
Equivalent
Carroll 2008 [35] Retrospective case control Post cancer treatment exercise only Experimental n=9
Control n=9
No Positive
Equivalent
Cnossen 2014 [22] Feasibility study Mode of program delivery Leaflet n=11
Booklet + DVD n=11
Online n=11
No N/A
Cnossen 2017 [24] Prospective clinical cohort study None n=50 Yes N/A
Duarte 2013 [36] Case series with chart review Noncompliant group Experimental n=57
Control n=28
Yes Positive
Equivalent
Govender 2020 [33] Two-arm parallel group non-blinded randomized feasibility trial Usual care Experimental n=16
Control n=16
Yes N/A
Guillen-Sola 2019 [26] Protocol for a single-blind randomized clinical trial Late intervention (immediately after CRT completion) Proposed 1:1 recruitment Yes N/A
Hajdu 2019 [27] Randomized Control Trial None (reports on adherence within the experimental group of a randomized control trial) n=45 N/A N/A
Hutcheson 2013 [42] Retrospective observational study Non-adherent group Experimental n=286
Control n=211
No Positive
Kotz 2012 [16] Randomized controlled trial Usual care Experimental n=13
Control n=13
Yes Positive
Kraaijenga 2015 [23] Randomized controlled trial Repeated Measures Baseline n=55
2 year n=29
6 year n=22
Yes Positive
Kulbersh 2006 [17] Prospective cohort study and cross-sectional QOL analysis Post treatment exercise (first visit after the initiation of their treatment). Experimental n=25
Control n=12
No Positive
Equivalent
Mashhour 2018 [28] Comparative study Not defined Experimental n=30 Control n=30 Yes Positive
Equivalent
Messing 2017 [25] Randomized controlled trial Usual care Experimental n=30
Control n=30
Yes Positive
Equivalent
Mortensen 2015 [18] Randomized controlled trial Usual care Experimental n=22
Control n=22
Yes Equivalent with positive trends
Ohba 2016 [37] Retrospective case-control design Exercise provided when dysphagia developed Experimental n=21
Control n=30
Yes Positive
Peng 2015 [40] Retrospective case series Prior to initiation of Swallowing Preservation Protocol (SPP) and those not enrolled once SPP was initiated Experimental n=41
Control n=66
Yes Positive
Retel 2011 [41] Retrospective cost-effectiveness analysis Usual Care Experimental n=37
Control n=53
No Positive
Shinn 2013 [39] Retrospective None n=109 No N/A
Starmer 2018 [34] Feasibility trial None n=36 No N/A
Tang 2011 [19] Randomized controlled trial Usual Care Experimental n=22
Control n=21
Yes Positive
van der Molen 2011 [20] Randomized controlled trial Usual Care Experimental n=27
Control n=22
Yes Positive
Virani 2015 [21] Prospective alternate assignment and characteristic matching Repetitive swallows Experimental n=26
Control n=24
Yes Positive
Equivalent
Wall 2020 [31] Three-arm prospective stratified parallel group study with 1:1:1 random allocation. Repeated Measures Service delivery mode Technology n=25
Clinician directed n=25
Patient directed n=27
Yes N/A
Wells 2016 [29] Feasibility study using quantitative and qualitative research methods within a quasi-experimental design Usual Care Proposed:
Experimental n=40
Control n=30
Yes N/A