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Table 1 Participants biomarkers and symptom levels on both diets, high salicylate and low salicylate

From: Effect of low salicylate diet on clinical and inflammatory markers in patients with aspirin exacerbated respiratory disease – a randomized crossover trial

 

Baseline

HS

LS

 

Post

Δ High

Post

Δ Low

Δ High x Δ Low

Median

IQR

Median

IQR

Median

IQR

Median

IQR

Median

IQR

p

Urinary SA

2.62

4.5

0.92

0.8

−1.7

3.0

0.6

3.4

−1.13

2.1

0.338

Urinary SU

37.9

45.6

23.82

54.3

−16.76

31.6

44.21

34.6

−7.35

19.3

0.482

Urinary CysLT

819.88

2649.6

771.99

1327.9

− 173.17

1065.2

874.05

1221.4

− 184.58

1518.9

0.949

Urinary Cr

10.3

11.3

*15.3

12.6

2.6

8.4

9.9

11.3

−0.3

11.1

0.655

SNOT - 22

66

40

64

40

7

15

*44

31

−10

24

0.013

  1. HS High-Salicylate Diet, LS Low-Salicylate Diet, SA Salicylic Acid (ng/ml), SU Salicyluric Acid (ng/ml), CysLT Cysteinyl leukotrienes (pg/ml), Cr Creatine (mmol/L), SNOT − 22 Sino-nasal outcome test, Δ High Post - Baseline of High-Salicylate diet group, Δ Low Post - Baseline of Low-salicylate diet group. * significance p ≤ 0.05 (Wilcoxon Test; baseline x post); Δ High x Δ Low = intergroup dietary effect comparison (Mann Whitney U test)