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Table 2 Current State of Ototoxicity Monitoring

From: Insight into the current practice of ototoxicity monitoring during cisplatin therapy

  

All Malignancies

 

All malignancies

(n = 379)

Head and Neck

(n = 122)

Non-Head and Neck (n = 257)

 

N (%)

N (%)

N (%)

P value*

Prior to treatment with cisplatin

 Counselled about ototoxicity risk

196 (51.7)

103 (84.4)

93 (36.2)

P < .0001

 Baseline pre-treatment audiogram ordered

92 (24.3)

70 (57.4)

22 (8.5)

P < .0001

During cisplatin treatment

 Otologic Complaints

91 (24)

51 (41.8)

43 (16.7)

P < .0001

  Treatment changed following otologic complaints

25 (27.5)

15 (29.4)

10 (23.2)

P = .5010

 Audiogram ordered during treatment

17 (4.5)

6 (5.0)

11 (4.3)

**P = .7937

Following cisplatin treatment

 Otologic Complaints (total)

130 (34.2)

75 (61.5)

55 (40)

P < .0001

 1-month post-treatment audiogram

20 (7.8)

13 (10.6)

7 (2.7)

**P = .0024

 3-month post-treatment audiogram

13 (5.1)

11 (9.0)

2 (0.8)

**P = .0001

 6-month post-treatment audiogram

16 (6.2)

12 (9.8)

4 (1.6)

**P = .0004

 Audiogram or Otolaryngology Consult 6–24 months post treatment

38 (15)

22 (18)

16 (6.2)

P = .0003

  1. *P value used to compare Head and Neck Cancer and Non-Head and Neck Cancer Groups. Significance level set at p < .01, and results are bolded if statistically significant
  2. **Fisher exact test statistic value