Table 1 Characteristics of the include studies
Study | Design | Participants | Interventions | Follow-up | Outcomes | Primary Results | |
|---|---|---|---|---|---|---|---|
Experimental | Control | ||||||
Benecke 2001 [8] | Retrospective cohort study | Patients underwent tympanoplasty | ADM (human-derived), n = 20 | Autologous temporalis fascia, n = 20 | 6 months | Graft success rate; Audiometric tests(ABG) | ADM is a suitable material for TM grafting |
Min 2018 [26] | Retrospective cohort study | Patients with tympanic membrane perforation who underwent type I tympanoplasty | ADM (human-derived), n = 26 | Autologous tragal perichondrium, n = 27 | 3 months | Graft success rate; Operation time; Postoperative pain; Audiometric tests(ABG,BC) | Tympanoplasty using ADM can be achieved with similar postoperative results and less pain. |
Vos 2005 [27] | Retrospective cohort study | Patients underwent type I tympanoplasty without mastoidectomy or ossicular chain reconstruction | ADM (human-derived), n = 25 | Autologous temporalis fascia, n = 56; Autologous fascia plus cartilage reconstruction, n = 33 | Not report | Graft success rate; Audiometric tests(ABG); Complications | ADM is an effective TM graft when used in type I tympanoplasty |
Yang 2019 [28] | Retrospective cohort study | Patients of tympanic membrane perforations who underwent tympanoplasty | ADM (human-derived), n = 27 | Autologous tragal perichondrium, n = 34 | 6 months | Graft success rate; Operation time; Audiometric tests(ABG) | ADM can be recommended as an attractive alternative to cartilage grafts |
Fu 2017 [29] | Retrospective cohort study | Chronic suppurative otitis media patients underwent type I tympanoplasty | ADM (human-derived), n = 32 | Autologous temporalis fascia, n = 28 | 3 months | Graft success rate; Operation time; Postoperative pain Audiometric tests(ABG) | The effect of ADM for repairing tympanic membrane is similar to the temporalis fascia. |
Lee 2018 [22] | Prospective randomised controlled study | Patients who underwent type I tympanoplasty for tympanic membrane perforation | ADM (human-derived), n = 27 | Autologous tragal perichondrium, n = 33 | 6 months | Graft success rate; Operation time; Postoperative pain; Audiometric tests(ABG,AC,BC); Complications | ADM was shown to be an effective alternative to tragal perichondrium. |
Li 2014 [23] | Randomised controlled study | Middle ear cholesteatoma patients underwent tympanoplasty for tympanic membrane perforation | ADM (human-derived), n = 30 | Autologous temporalis fascia, n = 22 | 12 months | Graft success rate; Audiometric tests(ABG) | ADM was shown to be an effective alternative to the temporalis fascia |
Raj 2011 [24] | Prospective randomized unblinded controlled trial | chronic suppurative otitis media patients underwent type I tympanoplasty | ADM (human-derived), n = 20 | Autologous temporalis fascia, n = 20 | 3 months | Graft success rate; Operation time; Postoperative pain; Audiometric tests(ABG,BC) | ADM as graft material are comparable to temporalis fascia in terms of graft uptake and hearing improvement. |
Liao 2017 [25] | Randomised controlled study | Chronic suppurative otitis media patients undergoing tympanoplasty | ADM (human-derived), n = 18 | Tragus cartilage-perichondrium, n = 69; Mastoid process periosteum, n = 21; Temporalis fascia, n = 28 | 24 months | Graft success rate; Operation time; Audiometric tests(ABG) | ADM is suitable for small and medium-sized perforation. |