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Table 2 Characteristics of participants

From: Human-derived acellular dermal matrix may be an alternative to autologous grafts in tympanic membrane reconstruction: systematic review and meta-analysis

Study Country n Average age Causes of TM perforation Mean perforation size% ADM derivation Autologous grafts Type of surgery Anesthesia
Benecke 2001 [8] USA 40 NR NR NR human Temporalis fascia Type 1 tympanoplasty NR
Min 2018 [26] Korea 53 53.2 NR 22.90% human Tragal perichondrium Type 1 tympanoplasty Local anesthesia
Vos 2005 [27] USA 108 20 NR 45% human Multiple grafts Type 1 tympanoplasty General anesthesia
Yang 2019 [28] China 61 29.2 NR NR human Tragal perichondrium Type 1 tympanoplasty General anesthesia
Fu 2017 [29] China 60 31.5 Chronic suppurative otitis media NR human Temporalis fascia Type 1 tympanoplasty Local anesthesia
Lee 2018 [22] Korea 60 53.3 NR NR human Tragal perichondrium Type 1 tympanoplasty Local anesthesia
Li 2014 [23] China 52 53 Middle ear cholesteatoma NR human Temporalis fascia Type 1 tympanoplasty General anesthesia
Raj 2011 [24] India 40 NR Chronic suppurative otitis media NR human Temporalis fascia Type 1 tympanoplasty Local anesthesia
Liao 2017 [25] China 136 41 Chronic suppurative otitis media NR human Multiple grafts Type 1 tympanoplasty NR
  1. TM Tympanic membrane; ADM Acellular dermal matrix; NR Not report