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Table 1 Summary of the general characteristics of the cohort, classified by P16 status

From: Contralateral nodal failures in oropharyngeal cancers after TORS and unilateral neck management: a retrospective study

Covariate Full sample
(n = 32)
n (%)
P16 (-)
(n = 9)
n (%)
P16 ( +)
(n = 23)
n (%)
p-value
Gender     0.23
Female 9 (28) 4 (44) 5 (22)  
Male 23 (72) 5 (56) 18 (78)  
Age     0.69
Mean (sd) 58 (9.4) 56.5 (11.9) 58.6 (8.5)  
Median (Min,Max) 57.9 (37.1,74.1) 55.9 (37.1,74.1) 58 (44.2,71.5)  
Smoking Hx     0.092
Current 17 (53) 7 (78) 10 (43)  
Ex-smoker 7 (22) 2 (22) 5 (22)  
Non-smoker 8 (25) 0 (0) 8 (35)  
Pack years     0.019
Mean (sd) 22 (21.5) 36.2 (23.4) 16.4 (18.4)  
Median (Min,Max) 19 (0,80) 30 (10,80) 10 (0,60)  
Drinking Hx    0.001
Ex-drinker 3 (9) 3 (33) 0 (0)  
Heavy 6 (19) 4 (44) 2 (9)  
Light 9 (28) 2 (22) 7 (30)  
Moderate 2 (6) 0 (0) 2 (9)  
Non-drinker 11 (34) 0 (0) 11 (48)  
Unknown 1 (3) 0 (0) 1 (4)  
cT stage     0.035
T0 4 0 4  
T1 19 (72) 9 (100) 10 (61)  
T2 9 (28) 0 (0) 9 (39)  
cN stage     0.049
N0 15 (47) 7 (78) 8 (35)  
N1 17 (53) 2 (22) 15 (65)  
pT     0.77
1 21 (66) 7 (78) 14 (61)  
2 10 (31) 2 (22) 8 (35)  
3 1 (3) 0 (0) 1 (4)  
pN     0.43
0 13 (41) 5 (56) 8 (35)  
1 15 (47) 4 (44) 11 (48)  
x 4 (12) 0 (0) 4 (17)  
ENE     0.32
No 27 (96) 8 (89) 19 (100)  
Yes 1 (4) 1 (11) 0 (0)  
Missing 4 0 4  
PNI     1
No 30 (94) 9 (100) 21 (91)  
Yes 2 (6) 0 (0) 2 (9)  
LVI     1
No 26 (84) 8 (89) 18 (82)  
Yes 5 (16) 1 (11) 4 (18)  
Missing 1 0 1  
Histology grade     0.011
Mod. diff 13 (68) 9 (100) 4 (40)  
Poorly diff 6 (32) 0 (0) 6 (60)  
Missing 13 0 13  
Radiation treatment     0.38
No 23 (72) 8 (89) 15 (65)  
Yes 9 (28) 1 (11) 8 (35)  
Chemo     1
No 31 (97) 9 (100) 22 (96)  
Yes 1 (3) 0 (0) 1 (4)  
Site     0.65
BOT 6 (19) 1 (11) 5 (22)  
Tonsil 26 (81) 8 (89) 18 (78)  
Follow-up (months)     0.98
Mean (sd) 21.6 (15.6) 21.6 (14.4) 21.6 (15.6)  
Median (Min, Max) 15.6 (3.6, 51.6) 26.4 (3.6, 46.8) 13.2 (4.8, 51.6)  
  1. Statistically significant values are given in bold