Time cohort | OR (95% CI) | Probability | ||
---|---|---|---|---|
Pre-COVID-19 | COVID-19 | |||
Sex | ||||
Male | 5 (100%) | 8 (88.9%) | 0.56 (0.02; 15.06) | p = 1* |
Female | 0 | 1 (11.1%) | ||
Venous sinus thrombosis | ||||
Absent | 4 (80%) | 4(44.4%) | 5 (0.38; 64.38) | p = 0.3 |
Present | 1 (20%) | 5 (55.6%) | ||
Comorbidities | ||||
Other | 1 (20%) | 0 | N/A | p = 0.002** |
Cardiovascular | 1 (20%) | 5 (55.6%) | ||
Pulmonary | 1 (20%) | 2 (22.2%) | ||
None | 2 (40%) | 2 (22.2%) | ||
Intracranial complications | ||||
Meningitis | 2 (40%) | 1 (11.1%) | N/A | p = 0. 0.009** |
Brain abscess | 2 (40%) | 3 (33.3%) | ||
Venous sinus thrombosis | 0 | 2 (22.2%) | ||
Brain abscess or meningitis with sinus thrombosis | 1 (20%) | 3 (33.3%) | ||
Prior history of chronic otitis | ||||
Yes | 3 (60%) | 5 (55.56%) | 1.2 (0.13; 11.05) | p = 1F |
No | 2 (40%) | 4 (44.4%) | ||
Risk factors for coagulopathies | ||||
Yes | 1 (25%) | 7 (12.5%) | 0.05 (0.002; 1.04) | p = 0.067F |
No | 3 (75%) | 1 (87.5%) |
Median (IQR) | Median (IQR) | |||
---|---|---|---|---|
Age | 32 (19) | 50 (22) | N/A | p = 0.547UM |
PT | 14.75 (1.35) | 15.1 (3) | N/A | p = 0.699UM |
INR | 1.35 (0.13) | 1.39 (0.29) | N/A | p = 0.643UM |
APTT | 31 (2.5) | 32 (7) | N/A | p = 0.816UM |
WBC | 16.63 (4.92) | 16.45 (6.07) | N/A | p = 0.699UM |
PLT | 235 (224) | 377 (399) | N/A | p = 0.316UM |
Fibrinogen | 273 (378.5) | 336 (299) | N/A | p = 0.316UM |
D-dimers | 0.12 (0.56) | 0.77 (1.3) | N/A | p = 0.247UM |
CRP | 111.05 (164.8) | 147.4(180.8) | N/A | p = 0.758UM |
LDH | 134.5 (127) | 177 (44) | N/A | p = 0.316UM |
Total number of patients | N = 5 | N = 9 |