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Table 4 Comparison of nominal and non-nominal characteristics between patients with confirmed venous sinus thrombosis and the absence of thrombus

From: Intracranial otogenic complications in adults: new factors that influenced its onset, frequency and nature

 

Venous sinus thrombosis

OR (95% CI)

Probability

Absent

Present

Sex

    

Male

7 (87.5%)

6 (100%)

2.6 (0.09; 75.5)

p = 1*

Female

1 (12.5%)

0

  

Comorbidities

    

Other

1 (12.5%)

2 (33.3%)

N/A

P = 0.005**

Cardiovascular

4 (50%)

2 (33.3%)

  

Pulmonary

0

1 (16.67%)

  

None

3 (37.5%)

1 (16.67%)

  

Prior history of chronic otitis

    

Yes

5 (62.5%)

3 (50%)

5 (0.07; 5.136)

p = 1F

No

3 (37.5%)

3 (50%)

  

Risk factors for coagulopathies

    

Yes

4 (50%)

4 (66.6%)

0.5 ( 0.06; 4.47)

p = 0.627F

No

4 (50%)

2 (33.3%)

  
 

Median (IQR)

Median (IQR)

  

Age

41.5 (21)

48.5 (23)

N/A

p = 0.846UM

PT

14.15 (1.9)

17 (2)

 

p = 0.048UM

INR

1.29 (0.17)

1.57 (0.19)

 

p = 0.040UM

APTT

30.5 (3)

36 (9)

 

p = 0.162UM

WBC

16.63 (7.53)

16.45 (3.05)

 

p = 0.608UM

PLT

285.5 (345)

377 (438)

 

p = 0.826UM

Fibrinogen

285 (59)

600 (4)

 

p = 0.034UM

D-dimers

0.12 (0.16)

1.5 (1.18)

 

p = 0.010UM

CRP

72.7 (198.85)

165.8 (69.3)

 

p = 0.305UM

LDH

145.5 (84)

48.5 (34)

 

p = 0.213UM

Total number of patients

N = 8

N = 6

  
  1. Underline values indicate significant (p < 0.05)
  2. N/A – not applicable; IQR – Interquartile ratio; OR – Odds Ratio; 95% CI – Confidence Interval; PT – prothrombin time; INR – International normalised ratio; APTT – activated partial thromboplastin time; WBC – White Blood Cell Count; PLT – Platelets; CRP – C-reactive protein levels; LDH – Lactic Acid Dehydrogenase
  3. *Haldane-Anscombe correction to Fisher’s exact test was applied
  4. **Fisher’s exact test after Haldane-Anscombe correction with Freeman-Halton extension for 2 × 4 contingency tables was used
  5. FFisher’s exact test was used
  6. UMMann–Whitney U test for non-parametric data was utilised