Fig. 4

Overexpression of CASC15 resulted in accelerated LSCC cell proliferation through miR-365 and cyclin D1. Cell proliferation data analyzed by one-way ANOVA and Tukey test showed that, comparing with two controls, CASC15 and cyclin D1 overexpression led to promoted, while miR-365 overexpression led to inhibited LSCC cell proliferation, and miR-365 overexpression reduced the effects of CASC15 overexpression, C1, empty vector transfection, NC2, negative control miRNA transfection, (*, One-way ANOVA and Tukey test, p = 0.012)